Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis. (Q40030757)

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31 December 2019

title

Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis (English)

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31 December 2019

8

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author name string

Kirstine Roepstorff

1

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31 December 2019

Izabela Rasmussen

2

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31 December 2019

Makoto Sawada

3

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31 December 2019

Cristophe Cudre-Maroux

4

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31 December 2019

Patrick Salmon

5

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31 December 2019

Gary Bokoch

6

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31 December 2019

Bo van Deurs

7

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31 December 2019

language of work or name

English

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publication date

26 December 2007

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Journal of Biological Chemistry

31 December 2019

published in

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31 December 2019

volume

283

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issue

12

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page(s)

7983-7993

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Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation

31 December 2019

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Molecular basis for Rac2 regulation of phagocyte NADPH oxidase

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Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase

21 January 2018

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Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation

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Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

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Modulation of p47 PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase

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Akt Phosphorylates p47phoxand Mediates Respiratory Burst Activity in Human Neutrophils

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Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation

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A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites

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Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid

21 January 2018

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The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions

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P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

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Biology of the p21-activated kinases

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Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

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p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils

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Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase

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Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

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The HIV-1 Nef protein and phagocyte NADPH oxidase activation

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Serial analysis of gene expression in a microglial cell line

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Regulation of macropinocytosis by p21-activated kinase-1

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A role for atm in E-cadherin-mediated contact inhibition in epithelial cells.

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The phagocyte NADPH oxidase depends on cholesterol-enriched membrane microdomains for assembly

21 January 2018

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Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells

21 January 2018

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Temporal and spatial distribution of activated Pak1 in fibroblasts

21 January 2018

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p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

21 January 2018

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Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation

21 January 2018

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Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase

21 January 2018

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Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity.

21 January 2018

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Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production

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Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A, and a mitogen-activated protein kinase

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Identifiers

DOI

10.1074/JBC.M708281200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160398%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference