Akt Phosphorylates p47phoxand Mediates Respiratory Burst Activity in Human Neutrophils (Q44432151)

2 December 2017

Akt phosphorylates p47phox and mediates respiratory burst activity in human neutrophils (English)

1 reference

2 December 2017

Akt Phosphorylates p47phoxand Mediates Respiratory Burst Activity in Human Neutrophils (English)

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

31 December 2023

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1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

31 December 2023

author name string

Qingdan Chen

1

1 reference

2 December 2017

Saurabh Singh

4

1 reference

2 December 2017

Waseem Butt

5

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2 December 2017

David W. Powell

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12734380

31 December 2023

Madhavi J. Rane

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12734380

31 December 2023

Jon B. Klein

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12734380

31 December 2023

Kenneth R. McLeish

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12734380

31 December 2023

language of work or name

English

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publication date

1 May 2003

1 reference

2 December 2017

15 May 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12734380

full work available at URL

31 December 2023

published in

Journal of Immunology

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2 December 2017

170

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2 December 2017

5302-5308

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2 December 2017

10

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The neutrophil NADPH oxidase

2 December 2017

2

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Activation of the phagocyte NADPH oxidase protein p47(phox). Phosphorylation controls SH3 domain-dependent binding to p22(phox).

31 December 2023

3

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophils

31 December 2023

4

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Protein kinase C zeta phosphorylates a subset of selective sites of the NADPH oxidase component p47phox and participates in formyl peptide-mediated neutrophil respiratory burst

31 December 2023

5

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A, and a mitogen-activated protein kinase

31 December 2023

6

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304.

31 December 2023

7

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Activation of p38 in stimulated human neutrophils: phosphorylation of the oxidase component p47phox by p38 and ERK but not by JNK

31 December 2023

8

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Activation of the Neutrophil NADPH Oxidase Is Inhibited by SB 203580, a Specific Inhibitor of SAPK2/p38

31 December 2023

9

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Differential mitogen-activated protein kinase stimulation by Fc gamma receptor IIa and Fc gamma receptor IIIb determines the activation phenotype of human neutrophils

31 December 2023

10

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Bacterial phagocytosis activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in human neutrophils

31 December 2023

12

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.

31 December 2023

14

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Phosphatidic acid-mediated phosphorylation of the NADPH oxidase component p47-phox. Evidence that phosphatidic acid may activate a novel protein kinase.

31 December 2023

15

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

31 December 2023

18

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils

31 December 2023

19

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

31 December 2023

20

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

31 December 2023

21

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

31 December 2023

22

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Phosphatidylinositol 3-kinase controls antineutrophil cytoplasmic antibodies-induced respiratory burst in human neutrophils.

31 December 2023

23

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Activation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-alpha and GM-CSF

31 December 2023

24

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils

31 December 2023

25

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

31 December 2023

26

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways

31 December 2023

27

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Role of extracellular signal-regulated kinase and phosphatidylinositol-3 kinase in chemoattractant and LPS delay of constitutive neutrophil apoptosis

31 December 2023

28

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

31 December 2023

29

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

A motif-based profile scanning approach for genome-wide prediction of signaling pathways

31 December 2023

33

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

31 December 2023

34

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases

31 December 2023

35

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

31 December 2023

36

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

31 December 2023

37

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase

31 December 2023

38

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils

31 December 2023

39

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

A synthetic peptide containing a predominant protein kinase C site within p47phox inhibits the NADPH oxidase in intact neutrophils

31 December 2023

41

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis

31 December 2023

42

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

Activation of p47(PHOX), a cytosolic subunit of the leukocyte NADPH oxidase. Phosphorylation of ser-359 or ser-370 precedes phosphorylation at other sites and is required for activity.

31 December 2023

43

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https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5302

31 December 2023

Identifiers

1 reference

2 December 2017

1 reference