HNF4alpha is a crucial modulator of the cholesterol-dependent regulation of NPC1L1. (Q40035456)

16 September 2017

HNF4alpha is a crucial modulator of the cholesterol-dependent regulation of NPC1L1. (English)

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16 September 2017

Yuki Iwayanagi

1

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16 September 2017

Tappei Takada

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2

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16 September 2017

Hiroshi Suzuki

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3

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16 September 2017

language of work or name

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14 December 2007

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16 September 2017

Pharmaceutical Research

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16 September 2017

25

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16 September 2017

5

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16 September 2017

1134-1141

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Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: the role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein

16 September 2017

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12 December 2020

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

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12 December 2020

LXR alpha transactivates mouse organic solute transporter alpha and beta via IR-1 elements shared with FXR.

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12 December 2020

The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys

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12 December 2020

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

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12 December 2020

Ezetimibe (Zetia): a new type of lipid-lowering agent

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12 December 2020

Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

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12 December 2020

Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine

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12 December 2020

Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

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12 December 2020

Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8.

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12 December 2020

Contributions of Absorbed Dietary Cholesterol and Cholesterol Synthesized in Small Intestine to Hypercholesterolemia in Diabetic Rats

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12 December 2020

The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha

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12 December 2020

Fatty acid regulation of hepatic gene transcription.

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12 December 2020

Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4alpha (HNF4alpha) isoforms in human and rats

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12 December 2020

Positive regulation of the human macrophage stimulating protein gene transcription. Identification of a new hepatocyte nuclear factor-4 (HNF-4) binding element and evidence that indicates direct association between NF-Y and HNF-4.

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12 December 2020

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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12 December 2020

Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.

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12 December 2020

Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2.

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12 December 2020

Sterol regulatory element-binding protein-2 interacts with hepatocyte nuclear factor-4 to enhance sterol isomerase gene expression in hepatocytes

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12 December 2020

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

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12 December 2020

Role of human hepatocyte nuclear factor 4alpha in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA

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12 December 2020

Cholesterol metabolism in type 1 diabetes

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12 December 2020

Genes that affect cholesterol synthesis, cholesterol absorption, and chylomicron assembly: the relationship between the liver and intestine in control and streptozotosin diabetic rats.

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12 December 2020

SREBP transcription factors: master regulators of lipid homeostasis

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12 December 2020

Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.

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12 December 2020

Hepatocyte nuclear factor-4{alpha} regulates the human organic anion transporter 1 gene in the kidney

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12 December 2020

Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1.

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12 December 2020

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

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12 December 2020

10.1007/S11095-007-9496-9

Identifiers

DOI

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16 September 2017

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