Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents (Q40054238)

16 September 2017

title

Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents (English)

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16 September 2017

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I Youlyouz-Marfak

1

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16 September 2017

N Gachard

2

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16 September 2017

C Le Clorennec

3

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16 September 2017

I Najjar

4

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16 September 2017

F Baran-Marszak

5

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16 September 2017

L Reminieras

6

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16 September 2017

E May

7

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16 September 2017

G W Bornkamm

8

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16 September 2017

R Fagard

9

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16 September 2017

J Feuillard

10

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16 September 2017

publication date

9 November 2007

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Cell Death & Differentiation

16 September 2017

published in

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16 September 2017

volume

15

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16 September 2017

issue

2

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16 September 2017

page(s)

376-385

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Twenty years of p53 research: structural and functional aspects of the p53 protein

16 September 2017

cites work

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STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis

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Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells

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Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

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STAT1: a modulator of chemotherapy-induced apoptosis

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The role of STATs in transcriptional control and their impact on cellular function

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Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1.

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Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor

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Effect of p53 status and STAT1 on chemotherapy-induced, Fas-mediated apoptosis in colorectal cancer

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STAT1 as a key modulator of cell death

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Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells.

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Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

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Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.

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Interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively

21 January 2018

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STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage

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Hdmx modulates the outcome of p53 activation in human tumor cells

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

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Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells

21 January 2018

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P53-independent caspase-mediated apoptosis in human leukaemic cells is induced by a DNA minor groove binder with antineoplastic activity

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Homogeneous time-resolved fluorescence assay for identifying p53 interactions with its protein partners, directly in a cellular extract.

21 January 2018

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

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JAK-STAT signaling activated by Abl oncogenes

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C-Abl as a modulator of p53.

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Insights into selective activation of p53 DNA binding by c-Abl.

21 January 2018

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Treatment of chronic myeloid leukemia with imatinib mesylate

21 January 2018

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ATM: a mediator of multiple responses to genotoxic stress

21 January 2018

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Enabling death by the Abl tyrosine kinase: mechanisms for nuclear shuttling of c-Abl in response to DNA damage

21 January 2018

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Evolving molecular therapy for chronic myeloid leukaemia--are we on target?

21 January 2018

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Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

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Regulation of tumor suppressors by nuclear-cytoplasmic shuttling

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A weak signal for strong responses: interferon-alpha/beta revisited

21 January 2018

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EBV latency III immortalization program sensitizes B cells to induction of CD95-mediated apoptosis via LMP1: role of NF-kappaB, STAT1, and p53.

21 January 2018

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Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation

21 January 2018

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Accumulation of an inactive form of p53 protein in cells treated with TNF alpha

21 January 2018

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Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

21 January 2018

1 reference

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Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

21 January 2018

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DNA damage induces phosphorylation of the amino terminus of p53

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CDD.4402270

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Dimensions Publication ID

16 September 2017

1012219103

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