PAR-2 activation and LPS synergistically enhance inflammatory signaling in airway epithelial cells by raising PAR expression level and interleukin-8 release (Q40086023)

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scientific article published on 31 August 2007

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English	PAR-2 activation and LPS synergistically enhance inflammatory signaling in airway epithelial cells by raising PAR expression level and interleukin-8 release	scientific article published on 31 August 2007

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scholarly article

1 reference

Europe PubMed Central

17 September 2017

PAR-2 activation and LPS synergistically enhance inflammatory signaling in airway epithelial cells by raising PAR expression level and interleukin-8 release (English)

1 reference

Europe PubMed Central

17 September 2017

author name string

Ewa Ostrowska

1

1 reference

Europe PubMed Central

17 September 2017

Elena Sokolova

2

1 reference

Europe PubMed Central

17 September 2017

Georg Reiser

3

1 reference

Europe PubMed Central

17 September 2017

publication date

31 August 2007

1 reference

Europe PubMed Central

17 September 2017

American Journal of Physiology - Lung Cellular and Molecular Physiology

1 reference

Europe PubMed Central

17 September 2017

293

1 reference

Europe PubMed Central

17 September 2017

5

1 reference

Europe PubMed Central

17 September 2017

L1208-18

1 reference

Europe PubMed Central

17 September 2017

The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Pseudomonas aeruginosa elastase stimulates ERK signaling pathway and enhances IL-8 production by alveolar epithelial cells in culture

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Inflammatory cytokines in cystic fibrosis lungs

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Asthma. From bronchoconstriction to airways inflammation and remodeling

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

The role of the mast cell in the pathophysiology of asthma

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Tryptase activates phosphatidylinositol 3-kinases proteolytically independently from proteinase-activated receptor-2 in cultured dog airway smooth muscle cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

High expression of pulmonary proteinase-activated receptor 2 in acute and chronic lung injury in preterm infants

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Neutrophil elastase induces IL-8 synthesis by lung epithelial cells via the mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Mold allergen, pen C 13, induces IL-8 expression in human airway epithelial cells by activating protease-activated receptor 1 and 2

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Protease-activated receptor-2-mediated inhibition of ion transport in human bronchial epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Lipopolysaccharide signaling in endothelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Stimulation of protease-activated receptor-2 inhibits airway eosinophilia, hyperresponsiveness and bronchoconstriction in a murine model of allergic inflammation.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Proteinase-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Pathogenesis of the pseudomonas lung lesion in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Inflammatory conditions increase expression of protease-activated receptor-2 by human airway smooth muscle cells in culture.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Differential expression of protease-activated receptors 1, 2, and 4 on human endothelial cells from different vascular sites

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

LPS induction of gene expression in human monocytes

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Tethered ligand-derived peptides of proteinase-activated receptor 3 (PAR3) activate PAR1 and PAR2 in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Proteinase-mediated signaling: Proteinase-activated receptors (PARs) and much more

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Protease-dependent activation of epithelial cells by fungal allergens leads to morphologic changes and cytokine production

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Proteinase-activated receptors (PARs)--the PAR3 Neo-N-terminal peptide TFRGAP interacts with PAR1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Signal transduction for proteinase-activated receptor-2-triggered prostaglandin E2 formation in human lung epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Lack of effect of proteinase-activated receptor-2 (PAR-2) deletion on the pathophysiological changes produced by lipopolysaccharide in the mouse: comparison with dexamethasone.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

The potential of various lipopolysaccharides to release IL-8 and G-CSF.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Control of ion transport in mammalian airways by protease activated receptors type 2 (PAR-2).

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Altered expression and in vivo lung function of protease-activated receptors during influenza A virus infection in mice.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Role of protease-activated receptors in airway function: a target for therapeutic intervention?

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Delayed onset of inflammation in protease-activated receptor-2-deficient mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Respiratory epithelial cells require Toll-like receptor 4 for induction of human beta-defensin 2 by lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Human airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Expression of protease activated receptor-2 (PAR-2) in central airways of smokers and non-smokers.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

A protective role for proteinase activated receptor 2 in airways of lipopolysaccharide-treated rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

The role of protease activation of inflammation in allergic respiratory diseases

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Induction of CXC chemokines in A549 airway epithelial cells by trypsin and staphylococcal proteases - a possible route for neutrophilic inflammation in chronic rhinosinusitis

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Agonists of proteinase-activated receptor 2 induce cytokine release and activation of nuclear transcription factor kappaB in human dermal microvascular endothelial cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kappa B and activator protein-2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Protease-activated receptor-1 in human lung fibroblasts mediates a negative feedback downregulation via prostaglandin E2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

A novel therapeutic target in various lung diseases: airway proteases and protease-activated receptors

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Abrogation of bronchial eosinophilic inflammation and attenuated eotaxin content in protease-activated receptor 2-deficient mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

The inflammatory response in humans after inhalation of bacterial endotoxin: a review

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Airway epithelial cells release eosinophil survival-promoting factors (GM-CSF) after stimulation of proteinase-activated receptor 2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Proteinase-activated receptor-2-mediated matrix metalloproteinase-9 release from airway epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

PAR2 activation interrupts E-cadherin adhesion and compromises the airway epithelial barrier: protective effect of beta-agonists.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Involvement of Rho signaling in PAR2-mediated regulation of neutrophil adhesion to lung epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Association of trypsin-2 with activation of gelatinase B and collagenase-2 in human bronchoalveolar lavage fluidin vivo

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

A protective role for protease-activated receptors in the airways

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00137.2007

21 January 2018

Identifiers

10.1152/AJPLUNG.00137.2007

1 reference

Europe PubMed Central

17 September 2017

1 reference

Europe PubMed Central

17 September 2017

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