Computer-aided prediction of QT-prolongation (Q40118144)

17 September 2017

title

Computer-aided prediction of QT-prolongation (English)

1 reference

17 September 2017

A Lagunin

2

0 references

Dmitry Filimonov

object named as

D Filimonov

series ordinal

3

0 references

Vladimir Poroikov

object named as

V Poroikov

series ordinal

4

0 references

Olga Tarasova

1 reference

ORCID Public Data File 2021

author name string

O Filz

series ordinal

1

1 reference

17 September 2017

publication date

1 January 2008

1 reference

SAR and QSAR in Environmental Research

17 September 2017

published in

1 reference

17 September 2017

volume

19

1 reference

17 September 2017

issue

1-2

1 reference

17 September 2017

page(s)

81-90

1 reference

hERG potassium channels and cardiac arrhythmia

17 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Predictive in silico modeling for hERG channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Medicinal chemistry of hERG optimizations: Highlights and hang-ups

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

A virtual screening method for prediction of the HERG potassium channel liability of compound libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Understanding the Structure−Activity Relationship of the Human Ether-a-go-go-Related Gene Cardiac K+ Channel. A Model for Bad Behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

A model for identifying HERG K+ channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Physicochemical features of the HERG channel drug binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Exploring blocker binding to a homology model of the open hERG K+ channel using docking and molecular dynamics methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

A QSAR model of HERG binding using a large, diverse, and internally consistent training set.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Prediction of hERG potassium channel affinity by the CODESSA approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Determination of hERG channel blockers using a decision tree

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Transgenic insulin released from G cells preferentially signals in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Understanding hERG inhibition with QSAR models based on a one-dimensional molecular representation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

In silico modelling of ADMET-a minireview of work from 2000 to 2004.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Greater than the sum of its parts: combining models for useful ADMET prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Predicting drug-hERG channel interactions that cause acquired long QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Prediction of biological activity spectra via the Internet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Blockade of HERG channels by HIV protease inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Differential effect of HERG blocking agents on cardiac electrical alternans in the guinea pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Developing a strategy for the nonclinical assessment of proarrhythmic risk of pharmaceuticals due to prolonged ventricular repolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Antimalarial drugs inhibit the acetylcholine-receptor-operated potassium current in atrial myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Cardiotoxicity of new antihistamines and cisapride

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Inhibition of HERG potassium channel current by the class 1a antiarrhythmic agent disopyramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Calcium, a signaling molecule in the endoplasmic reticulum?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Drug-induced QT prolongation in women during the menstrual cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Insights for Human Ether-a-Go-Go-Related Gene Potassium Channel Inhibition Using Recursive Partitioning and Kohonen and Sammon Mapping Techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

PASS: identification of probable targets and mechanisms of toxicity†

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

Characterization of binding site of closed-state KCNQ1 potassium channel by homology modeling, molecular docking, and pharmacophore identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10629360701844183

10.1080/10629360701844183

21 January 2018

Identifiers

DOI

1 reference

17 September 2017

1 reference