Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation (Q40134407)

17 September 2017

Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation (English)

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17 September 2017

9

Rose M Cubbon

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17 September 2017

15

Andrea Carfi

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17 September 2017

Timothy S Fisher

1

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17 September 2017

Paola Lo Surdo

2

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17 September 2017

Shilpa Pandit

3

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17 September 2017

Marco Mattu

4

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17 September 2017

Joseph C Santoro

5

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17 September 2017

Doug Wisniewski

6

1 reference

17 September 2017

Richard T Cummings

7

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17 September 2017

Alessandra Calzetta

8

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17 September 2017

Paul A Fischer

10

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17 September 2017

Anil Tarachandani

11

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17 September 2017

Raffaele De Francesco

12

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17 September 2017

Samuel D Wright

13

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17 September 2017

Carl P Sparrow

14

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17 September 2017

Ayesha Sitlani

16

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17 September 2017

language of work or name

English

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publication date

10 May 2007

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Journal of Biological Chemistry

17 September 2017

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17 September 2017

282

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17 September 2017

20502-20512

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17 September 2017

28

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The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

17 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

The proprotein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Functional characterization of Narc 1, a novel proteinase related to proteinase K

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Label-free screening of bio-molecular interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

SPR for molecular interaction analysis: a review of emerging application areas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

The proprotein convertases and their implication in sterol and/or lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Furin at the cutting edge: from protein traffic to embryogenesis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Recycling receptors: The round-trip itinerary of migrant membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Structure of the LDL receptor extracellular domain at endosomal pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Expression and localization of PCSK9 in rat hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Molecular biology of PCSK9: its role in LDL metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

The metabolism in vitro of human low-density lipoprotein by the human hepatoma cell line Hep G2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene: long-term follow-up and treatment response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701634200

21 January 2018

Identifiers

DOI

10.1074/JBC.M701634200

1 reference

17 September 2017

1 reference