Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease. (Q40149501)

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28 December 2019

title

Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease (English)

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28 December 2019

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4

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28 December 2019

Lynn A Raymond

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28 December 2019

author name string

Mannie M Y Fan

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28 December 2019

Herman B Fernandes

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28 December 2019

Lily Y J Zhang

3

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28 December 2019

language of work or name

English

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publication date

1 April 2007

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28 December 2019

published in

Journal of Neuroscience

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28 December 2019

volume

27

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28 December 2019

issue

14

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28 December 2019

page(s)

3768-3779

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Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin

28 December 2019

cites work

1 reference

12 December 2020

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

12 December 2020

Alternative splicing of the C-terminal domain regulates cell surface expression of the NMDA receptor NR1 subunit

1 reference

12 December 2020

Localization of alternatively spliced NMDAR1 glutamate receptor isoforms in rat striatal neurons

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12 December 2020

D1 dopamine receptor-induced cyclic AMP-dependent protein kinase phosphorylation and potentiation of striatal glutamate receptors

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12 December 2020

Native N-methyl-D-aspartate receptors containing NR2A and NR2B subunits have pharmacologically distinct competitive antagonist binding sites

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12 December 2020

Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis.

1 reference

12 December 2020

Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization

1 reference

12 December 2020

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

1 reference

12 December 2020

Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting

1 reference

12 December 2020

Mutant huntingtin enhances excitotoxic cell death.

1 reference

12 December 2020

Protein kinase C modulates NMDA receptor trafficking and gating

1 reference

12 December 2020

The selective vulnerability of nerve cells in Huntington's disease

1 reference

12 December 2020

An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing.

1 reference

12 December 2020

NMDA receptor subunits: diversity, development and disease

1 reference

12 December 2020

Dopamine D1 receptor-dependent trafficking of striatal NMDA glutamate receptors to the postsynaptic membrane.

1 reference

12 December 2020

Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene

1 reference

12 December 2020

NMDA receptor function in mouse models of Huntington disease

1 reference

12 December 2020

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

1 reference

12 December 2020

Mobile NMDA receptors at hippocampal synapses

1 reference

12 December 2020

The Yin and Yang of NMDA receptor signalling

1 reference

12 December 2020

Trafficking of NMDA receptors

1 reference

12 December 2020

Activity-dependent mRNA splicing controls ER export and synaptic delivery of NMDA receptors

1 reference

12 December 2020

Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington disease

1 reference

12 December 2020

Developmental decrease in NMDA receptor desensitization associated with shift to synapse and interaction with postsynaptic density-95.

1 reference

12 December 2020

The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin.

1 reference

12 December 2020

N-Methyl-D-aspartate receptors: subunit assembly and trafficking to the synapse

1 reference

12 December 2020

Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease

1 reference

12 December 2020

Postsynaptic density protein-95 regulates NMDA channel gating and surface expression.

1 reference

12 December 2020

Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease

1 reference

12 December 2020

Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis

1 reference

12 December 2020

Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions

1 reference

12 December 2020

Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease

1 reference

12 December 2020

Altered cortical glutamate receptor function in the R6/2 model of Huntington's disease

1 reference

12 December 2020

Wild-type huntingtin protects neurons from excitotoxicity

1 reference

12 December 2020

Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421.

1 reference

12 December 2020

Changes in expression of N-methyl-D-aspartate receptor subunits occur early in the R6/2 mouse model of Huntington's disease

1 reference

12 December 2020

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

1 reference

12 December 2020

RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1.

1 reference

12 December 2020

AMPA and NMDA glutamate receptor trafficking: multiple roads for reaching and leaving the synapse

1 reference

12 December 2020

Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease

1 reference

12 December 2020

Excitotoxic injury of the neostriatum: a model for Huntington's disease

1 reference

12 December 2020

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease

1 reference

12 December 2020

A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon

1 reference

12 December 2020

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1 reference

12 December 2020

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels

1 reference

12 December 2020

The quinolinic acid model of Huntington's disease: locomotor abnormalities

1 reference

12 December 2020

NMDA receptor losses in putamen from patients with Huntington's disease

1 reference

12 December 2020

Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95

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12 December 2020

NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum.

1 reference

12 December 2020

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

12 December 2020

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

1 reference

12 December 2020

Molecular biology of glutamate receptors.

1 reference

12 December 2020

Cloned glutamate receptors

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12 December 2020

Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation

1 reference

12 December 2020

Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization

1 reference

12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size

1 reference

12 December 2020

Postsynaptic membrane fusion and long-term potentiation

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12 December 2020

1 reference

12 December 2020

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

1 reference

12 December 2020

10.1523/JNEUROSCI.4356-06.2007

Identifiers

DOI

1 reference

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28 December 2019

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28 December 2019

PubMed publication ID

17409241

1 reference