Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C delta pathway (Q40166045)

18 September 2017

Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C delta pathway (English)

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18 September 2017

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Yutong Wang

1

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PubMed ID

17325386

18 September 2017

John F Oram

series ordinal

2

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PubMed ID

17325386

18 September 2017

language of work or name

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26 February 2007

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Journal of Lipid Research

18 September 2017

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18 September 2017

48

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18 September 2017

1062-1068

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18 September 2017

5

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Study of ABCA1 function in transgenic mice

18 September 2017

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ABCA1-deficient mice: insights into the role of monocyte lipid efflux in HDL formation and inflammation

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Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations

21 January 2018

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ATP-binding cassette transporter A1: a cell cholesterol exporter that protects against cardiovascular disease

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Regulation and Mechanisms of ATP-Binding Cassette Transporter A1-Mediated Cellular Cholesterol Efflux

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Cloning of two novel ABC transporters mapping on human chromosome 9

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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

21 January 2018

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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

21 January 2018

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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 January 2018

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The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

21 January 2018

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Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.

21 January 2018

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ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR.

21 January 2018

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Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

21 January 2018

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Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

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Regulation and activity of the human ABCA1 gene in transgenic mice

21 January 2018

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Cyclic AMP induces apolipoprotein E binding activity and promotes cholesterol efflux from a macrophage cell line to apolipoprotein acceptors

21 January 2018

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ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

21 January 2018

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The correlation of ATP-binding cassette 1 mRNA levels with cholesterol efflux from various cell lines

21 January 2018

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Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I

21 January 2018

1 reference

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Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly

21 January 2018

1 reference

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Protein kinase A site-specific phosphorylation regulates ATP-binding cassette A1 (ABCA1)-mediated phospholipid efflux.

21 January 2018

1 reference

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Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter

21 January 2018

1 reference

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Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol

21 January 2018

1 reference

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Unsaturated fatty acids inhibit cholesterol efflux from macrophages by increasing degradation of ATP-binding cassette transporter A1.

21 January 2018

1 reference

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Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway

21 January 2018

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Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

21 January 2018

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ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions

21 January 2018

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Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol

21 January 2018

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Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cdelta.

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Oleic acid-induced PKC isozyme translocation in RAW 264.7 macrophages

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Distinctive activation mechanisms and functions for protein kinase Cdelta

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Secretions of MMP-9 by soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) mediated by protein kinase C (PKC)delta and phospholipase D (PLD) in murine macrophage

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LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1

21 January 2018

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

21 January 2018

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Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action

21 January 2018

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

21 January 2018

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ATP-binding cassette transporter A1 expression disrupts raft membrane microdomains through its ATPase-related functions.

21 January 2018

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ABCA1 mRNA and protein distribution patterns predict multiple different roles and levels of regulation

21 January 2018

1 reference

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Homozygous Tangier disease and cardiovascular disease

21 January 2018

1 reference

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Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor-α secretion in Abca1-deficient macrophages

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10.1194/JLR.M600437-JLR200

21 January 2018

Identifiers

DOI

1 reference

18 September 2017

1 reference

PubMed ID

17325386