Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells. (Q40180678)

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24 December 2019

title

Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells (English)

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24 December 2019

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1

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24 December 2019

author name string

James Sinnett-Smith

series ordinal

2

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24 December 2019

Enrique Rozengurt

series ordinal

3

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24 December 2019

publication date

22 November 2006

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24 December 2019

number of pages

11

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inferred from page(s)

published in

Cellular Signalling

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24 December 2019

volume

19

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24 December 2019

issue

5

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24 December 2019

page(s)

1000-1010

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RNA interference reveals a differential role of FAK and Pyk2 in cell migration, leading edge formation and increase in focal adhesions induced by LPA in intestinal epithelial cells

24 December 2019

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Bombesin and angiotensin II rapidly stimulate Src phosphorylation at Tyr-418 in fibroblasts and intestinal epithelial cells through a PP2-insensitive pathway

22 September 2017

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22 September 2017

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Hyperosmotic stress induces rapid focal adhesion kinase phosphorylation at tyrosines 397 and 577. Role of Src family kinases and Rho family GTPases

22 September 2017

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22 September 2017

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22 September 2017

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FAK regulates biological processes important for the pathogenesis of cancer

22 September 2017

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Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression

22 September 2017

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Focal adhesion kinase: the first ten years

22 September 2017

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ANG II stimulates PKC-dependent ERK activation, DNA synthesis, and cell division in intestinal epithelial cells

22 September 2017

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Differential regulation of cell motility and invasion by FAK

22 September 2017

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Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells

22 September 2017

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Biochemical signals and biological responses elicited by the focal adhesion kinase

22 September 2017

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Serine phosphorylation of focal adhesion kinase in interphase and mitosis: a possible role in modulating binding to p130(Cas).

22 September 2017

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Lysophosphatidic acid receptors

22 September 2017

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FAK integrates growth-factor and integrin signals to promote cell migration

22 September 2017

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Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

22 September 2017

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Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

22 September 2017

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Signaling through focal adhesion kinase

22 September 2017

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Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists

22 September 2017

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Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAK

22 September 2017

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Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

22 September 2017

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Inhibition of pp125FAK in cultured fibroblasts results in apoptosis

22 September 2017

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Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

22 September 2017

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22 September 2017

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Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

22 September 2017

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22 September 2017

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22 September 2017

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

22 September 2017

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22 September 2017

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22 September 2017

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Angiotensin II activates at least two tyrosine kinases in rat liver epithelial cells. Separation of the major calcium-regulated tyrosine kinase from p125FAK.

22 September 2017

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Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes

22 September 2017

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Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion

22 September 2017

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ANG II and LPA induce Pyk2 tyrosine phosphorylation in intestinal epithelial cells: role of Ca2+, PKC, and Rho kinase

25 September 2017

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PKD in intestinal epithelial cells: rapid activation by phorbol esters, LPA, and angiotensin through PKC.

25 September 2017

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Focal adhesion kinase: at the crossroads of signal transduction.

25 September 2017

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Signaling through focal adhesion kinase

25 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868572

G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II.

25 September 2017

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PDGF and FGF induce focal adhesion kinase (FAK) phosphorylation at Ser-910: dissociation from Tyr-397 phosphorylation and requirement for ERK activation

15 June 2018

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Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation

15 June 2018

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Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate.

15 June 2018

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Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide

15 June 2018

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Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer

15 June 2018

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Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells

15 June 2018

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Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.

20 August 2018

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Sustained tyrosine-phosphorylation of FAK through Rho-dependent adhesion to fibronectin is essential for cancer cell migration

20 August 2018

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Bombesin and platelet-derived growth factor induce association of endogenous focal adhesion kinase with Src in intact Swiss 3T3 cells

20 August 2018

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Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion

20 August 2018

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Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells

20 August 2018

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12 December 2020

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn

1 reference

12 December 2020

Alpha integrin subunits regulate human (Caco-2) intestinal epithelial proliferation and phenotype

1 reference

12 December 2020

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

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12 December 2020

A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II

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12 December 2020

10.1016/J.CELLSIG.2006.11.004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17240116%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17240116%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

PubMed publication ID

17240116

1 reference