Physical and functional interaction of the p14ARF tumor suppressor with ribosomes (Q40221220)

18 September 2017

Physical and functional interaction of the p14ARF tumor suppressor with ribosomes (English)

1 reference

18 September 2017

Helen Rizos

1

1 reference

18 September 2017

Heather A McKenzie

2

1 reference

18 September 2017

Ana Luisa Ayub

3

1 reference

18 September 2017

Sarah Woodruff

4

1 reference

18 September 2017

Therese M Becker

5

1 reference

18 September 2017

Lyndee L Scurr

6

1 reference

18 September 2017

Joachim Stahl

7

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18 September 2017

Richard F Kefford

8

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18 September 2017

language of work or name

English

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publication date

11 October 2006

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Journal of Biological Chemistry

18 September 2017

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18 September 2017

281

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18 September 2017

49

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18 September 2017

38080-38088

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Genetic testing for melanoma.

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

A mutation hotspot at the p14ARF splice site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Comprehensive analysis of CDKN2A (p16INK4A/p14ARF) and CDKN2B genes in 53 melanoma index cases considered to be at heightened risk of melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

ARF function does not require p53 stabilization or Mdm2 relocalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Inhibition of HDM2 and activation of p53 by ribosomal protein L23

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Stability of nucleolar versus non-nucleolar forms of human p14(ARF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Preferential cleavage in pre-ribosomal RNA byprotein B23 endoribonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

DNA damage disrupts the p14ARF-B23(nucleophosmin) interaction and triggers a transient subnuclear redistribution of p14ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Bop1 is a mouse WD40 repeat nucleolar protein involved in 28S and 5. 8S RRNA processing and 60S ribosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

p53 functions as a cell cycle control protein in osteosarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

p19ARF targets certain E2F species for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

eIF2 and the control of cell physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Protein NPM3 interacts with the multifunctional nucleolar protein B23/nucleophosmin and inhibits ribosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Upregulated expression of the genes encoding translation initiation factors eIF-4E and eIF-2alpha in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

The role of translation in neoplastic transformation from a pathologist's point of view

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

p19ARF directly and differentially controls the functions of c-Myc independently of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Nucleolin functions in the first step of ribosomal RNA processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

p53-independent functions of the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Cytoplasmic complex of p53 and eEF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

Mutations in theINK4a/ARFMelanoma Susceptibility Locus Functionally Impair p14ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609405200

21 January 2018

Identifiers

DOI

10.1074/JBC.M609405200

1 reference

18 September 2017

1 reference