Stability of nucleolar versus non-nucleolar forms of human p14(ARF). (Q40529860)

21 September 2017

Stability of nucleolar versus non-nucleolar forms of human p14(ARF). (English)

1 reference

21 September 2017

Helen Rodway

1

1 reference

21 September 2017

Susana Llanos

series ordinal

2

1 reference

21 September 2017

Janice Rowe

series ordinal

3

1 reference

21 September 2017

Gordon Peters

series ordinal

4

1 reference

21 September 2017

language of work or name

English

0 references

publication date

1 August 2004

1 reference

21 September 2017

1 reference

21 September 2017

23

1 reference

21 September 2017

37

1 reference

21 September 2017

6186-6192

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207854

21 September 2017

0 references

cites work

Defining the molecular basis of Arf and Hdm2 interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

p19ARF targets certain E2F species for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

Ubiquitin-independent proteolytic functions of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

Transcriptional regulation of the human tumor suppressor p14(ARF) by E2F1, E2F2, E2F3, and Sp1-like factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

Mutations in theINK4a/ARFMelanoma Susceptibility Locus Functionally Impair p14ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

Regulation of p53 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Differential regulation of E2F1, DP1, and the E2F1/DP1 complex by ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Human p14(Arf): an exquisite sensor of morphological changes and of short-lived perturbations in cell cycle and in nucleolar function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Human ARF binds E2F1 and inhibits its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

MdmX protects p53 from Mdm2-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Human ARF protein interacts with topoisomerase I and stimulates its activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Absence of p16INK4a and truncation of ARF tumor suppressors in chickens.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

ARF function does not require p53 stabilization or Mdm2 relocalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

The INK4a/ARF network in tumour suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

A proteasome howdunit: the case of the missing signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207854

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207854

1 reference

Dimensions Publication ID

21 September 2017

1030166593

0 references

Fatcat ID

release_rap3njayqjatxe6jvbivxm5lx4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rap3njayqjatxe6jvbivxm5lx4

24 November 2022

mapped directly with Wikidata item

1 reference