Role of amino acid side chains in region 17-31 of parathyroid hormone (PTH) in binding to the PTH receptor (Q40241176)

18 September 2017

title

Role of amino acid side chains in region 17-31 of parathyroid hormone (PTH) in binding to the PTH receptor (English)

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18 September 2017

5

Thomas J Gardella

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18 September 2017

Thomas Dean

1

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18 September 2017

Ashok Khatri

series ordinal

2

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18 September 2017

Zhanna Potetinova

series ordinal

3

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18 September 2017

Gordon E Willick

series ordinal

4

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18 September 2017

language of work or name

English

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publication date

21 August 2006

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Journal of Biological Chemistry

18 September 2017

published in

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18 September 2017

volume

281

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18 September 2017

issue

43

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18 September 2017

page(s)

32485-32495

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The physiology of parathyroid hormone-related protein

18 September 2017

cites work

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Solution structure of the osteogenic 1-31 fragment of the human parathyroid hormone

21 January 2018

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Backbone-methylated analogues of the principle receptor binding region of human parathyroid hormone. Evidence for binding to both the N-terminal extracellular domain and extracellular loop region

21 January 2018

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Active variants of human parathyroid hormone (1-34) with multiple amino acid substitutions

21 January 2018

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Parathyroid hormone and parathyroid hormone-related peptide, and their receptors

21 January 2018

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Evaluating the signal transduction mechanism of the parathyroid hormone 1 receptor. Effect of receptor-G-protein interaction on the ligand binding mechanism and receptor conformation

21 January 2018

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Peptide agonist docking in the N-terminal ectodomain of a class II G protein-coupled receptor, the VPAC1 receptor. Photoaffinity, NMR, and molecular modeling

21 January 2018

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NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor

21 January 2018

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The (1-14) fragment of parathyroid hormone (PTH) activates intact and amino-terminally truncated PTH-1 receptors

21 January 2018

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Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations

21 January 2018

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Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor

21 January 2018

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Evidence for a ligand interaction site at the amino-terminus of the parathyroid hormone (PTH)/PTH-related protein receptor from cross-linking and mutational studies

21 January 2018

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Multiple sites of contact between the carboxyl-terminal binding domain of PTHrP-(1--36) analogs and the amino-terminal extracellular domain of the PTH/PTHrP receptor identified by photoaffinity cross-linking

21 January 2018

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Residue 19 of the parathyroid hormone (PTH) modulates ligand interaction with the juxtamembrane region of the PTH-1 receptor

21 January 2018

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Structural requirements for conserved arginine of parathyroid hormone

21 January 2018

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Dual signaling and ligand selectivity of the human PTH/PTHrP receptor

21 January 2018

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Characterization and agonist-induced down-regulation of parathyroid hormone receptors in clonal rat osteosarcoma cells

21 January 2018

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Enhanced activity in parathyroid hormone-(1-14) and -(1-11): novel peptides for probing ligand-receptor interactions

21 January 2018

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A highly effective dominant negative alpha s construct containing mutations that affect distinct functions inhibits multiple Gs-coupled receptor signaling pathways

21 January 2018

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Novel parathyroid hormone (PTH) antagonists that bind to the juxtamembrane portion of the PTH/PTH-related protein receptor

21 January 2018

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Large differences in the helix propensities of alanine and glycine

21 January 2018

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Binding domain of human parathyroid hormone receptor: from conformation to function

21 January 2018

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Membrane lipid phase as catalyst for peptide-receptor interactions

21 January 2018

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Identification of a contact site for residue 19 of parathyroid hormone (PTH) and PTH-related protein analogs in transmembrane domain two of the type 1 PTH receptor

21 January 2018

1 reference

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Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution

21 January 2018

1 reference

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Stabilized NMR structure of the hypercalcemia of malignancy peptide PTHrP[Ala-26](1-34)amide

21 January 2018

1 reference

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Structure-function studies of analogues of parathyroid hormone (PTH)-1-34 containing beta-amino acid residues in positions 11-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606179200

The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606179200

21 January 2018

Identifiers

DOI

10.1074/JBC.M606179200

1 reference

18 September 2017

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