The pre-M1 segment of the alpha1 subunit is a transduction element in the activation of the GABAA receptor (Q40269814)

19 September 2017

title

The pre-M1 segment of the alpha1 subunit is a transduction element in the activation of the GABAA receptor (English)

1 reference

19 September 2017

Angelo Keramidas

1

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19 September 2017

Thomas L Kash

series ordinal

2

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19 September 2017

Neil L Harrison

series ordinal

3

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19 September 2017

language of work or name

English

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publication date

8 June 2006

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19 September 2017

published in

Journal of Physiology

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19 September 2017

volume

575

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19 September 2017

issue

Pt 1

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19 September 2017

page(s)

11-22

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Mechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure.

19 September 2017

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GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.

21 January 2018

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21 January 2018

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Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement

21 January 2018

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The activation mechanism of alpha1 homomeric glycine receptors

21 January 2018

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Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis.

21 January 2018

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Slow phases of GABA(A) receptor desensitization: structural determinants and possible relevance for synaptic function

21 January 2018

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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

21 January 2018

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A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists.

21 January 2018

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Gating dynamics of the acetylcholine receptor extracellular domain.

21 January 2018

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

21 January 2018

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Excision of membrane patches reduces the mean open time of nicotinic acetylcholine receptors

21 January 2018

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A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site

21 January 2018

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Investigation of the alpha(1)-glycine receptor channel-opening kinetics in the submillisecond time domain

21 January 2018

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The dissociation of acetylcholine from open nicotinic receptor channels

21 January 2018

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Mapping the conformational wave of acetylcholine receptor channel gating

21 January 2018

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Arginine 222 in the pre-transmembrane domain 1 of 5-HT3A receptors links agonist binding to channel gating

21 January 2018

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Charged Residues in the β2 Subunit Involved in GABAA Receptor Activation

21 January 2018

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Coupling of agonist binding to channel gating in the GABA(A) receptor

21 January 2018

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Structural elements involved in activation of the gamma-aminobutyric acid type A (GABAA) receptor

21 January 2018

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A cytoplasmic region determines single-channel conductance in 5-HT3 receptors

21 January 2018

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Principal pathway coupling agonist binding to channel gating in nicotinic receptors

21 January 2018

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Modes and models of GABA(A) receptor gating

21 January 2018

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Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes

21 January 2018

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Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

21 January 2018

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Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

21 January 2018

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How quickly can GABAA receptors open?

21 January 2018

1 reference

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Charged residues in the alpha1 and beta2 pre-M1 regions involved in GABAA receptor activation.

21 January 2018

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Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists

21 January 2018

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The GABAA receptor alpha 1 subunit Pro174-Asp191 segment is involved in GABA binding and channel gating

21 January 2018

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On the mechanism of a mutated and abnormally functioning gamma-aminobutyric acid (A) receptor linked to epilepsy

21 January 2018

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Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation

21 January 2018

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Modulation of GABA(A) receptor channel gating by pentobarbital

21 January 2018

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

21 January 2018

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An arginine involved in GABA binding and unbinding but not gating of the GABA(A) receptor.

21 January 2018

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Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation

21 January 2018

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A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors

21 January 2018

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Coupled and uncoupled gating and desensitization effects by pore domain mutations in GABA(A) receptors.

21 January 2018

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Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function.

14 September 2018

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Dominant gating governing transient GABA(A) receptor activity: a first latency and Po/o analysis.

14 September 2018

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Effects of halothane on GABA(A) receptor kinetics: evidence for slowed agonist unbinding.

14 September 2018

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Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.

14 September 2018

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The channel opening rate of adult- and fetal-type mouse muscle nicotinic receptors activated by acetylcholine

14 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16763005

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interaction at End-Plate Receptors between Different Choline Derivatives

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16763005

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1113/JPHYSIOL.2005.102756

1 reference

19 September 2017

0 references

1 reference