An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer. (Q40297038)

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18 January 2020

title

An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer (English)

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18 January 2020

3

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18 January 2020

Caterina Missero

10

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18 January 2020

Sandro Banfi

7

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18 January 2020

author name string

Dario Antonini

1

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18 January 2020

Barbara Rossi

2

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18 January 2020

Annunziata Minichiello

4

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18 January 2020

Tina Di Palma

5

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18 January 2020

Marcella Corrado

6

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18 January 2020

Mariastella Zannini

8

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18 January 2020

Janice L Brissette

9

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18 January 2020

language of work or name

English

0 references

publication date

1 April 2006

1 reference

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Molecular and Cellular Biology

18 January 2020

published in

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18 January 2020

volume

26

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18 January 2020

issue

8

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18 January 2020

page(s)

3308-3318

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IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium

18 January 2020

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p63 is the molecular switch for initiation of an epithelial stratification program

22 September 2017

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Positive and negative regulation of ΔN-p63 promoter activity by p53 and ΔN-p63-α contributes to differential regulation of p53 target genes

22 September 2017

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deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes

22 September 2017

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DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development

22 September 2017

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The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations

22 September 2017

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REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

22 September 2017

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Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains

22 September 2017

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A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

22 September 2017

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Loricrin expression in cultured human keratinocytes is controlled by a complex interplay between transcription factors of the Sp1, CREB, AP1, and AP2 families

22 September 2017

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Dissection of a complex enhancer element: maintenance of keratinocyte specificity but loss of differentiation specificity

22 September 2017

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Transcription factor AP-2 is an essential and direct regulator of epidermal development in Xenopus

22 September 2017

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22 September 2017

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Mutations in the p53 homolog p63: allele-specific developmental syndromes in humans.

22 September 2017

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Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

22 September 2017

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Identification and tissue distribution of novel KET/p63 splice variants

22 September 2017

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Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation.

22 September 2017

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Association of p63 with proliferative potential in normal and neoplastic human keratinocytes

15 June 2018

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Association between mouse nude gene expression and the initiation of epithelial terminal differentiation

15 June 2018

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Perp is a p63-regulated gene essential for epithelial integrity.

15 June 2018

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Phylogenetic estimation of context-dependent substitution rates by maximum likelihood

20 August 2018

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Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm

20 August 2018

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20 August 2018

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20 August 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/16581802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.26.8.3308-3318.2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16581802%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16581802%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference