Overexpression of von Hippel-Lindau tumor suppressor protein and antisense HIF-1alpha eradicates gliomas (Q40364565)

19 September 2017

Overexpression of von Hippel-Lindau tumor suppressor protein and antisense HIF-1alpha eradicates gliomas (English)

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19 September 2017

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X Sun

1

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19 September 2017

M Liu

2

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19 September 2017

Y Wei

3

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19 September 2017

F Liu

4

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19 September 2017

X Zhi

5

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19 September 2017

R Xu

6

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19 September 2017

G W Krissansen

7

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19 September 2017

1 April 2006

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19 September 2017

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19 September 2017

13

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4

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19 September 2017

428-435

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https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700907

19 September 2017

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cites work

Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1alpha.

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1alpha Pro-564 hydroxylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Protection against hypoxia-induced increase in blood-brain barrier permeability: role of tight junction proteins and NFkappaB.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Regression of solid tumors by engineered overexpression of von Hippel–Lindau tumor suppressor protein and antisense hypoxia-inducible factor-1α

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Estrogen attenuates oxidative stress-induced apoptosis in C6 glial cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Roles of BCL-2 and caspase 3 in the adenosine A3 receptor-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Relevance of nuclear and cytoplasmic von hippel lindau protein expression for renal carcinoma progression.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Role of nuclear and cytoplasmic localization in the tumour-suppressor activity of the von Hippel-Lindau protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Parathyroid hormone-related protein is an essential growth factor for human clear cell renal carcinoma and a target for the von Hippel-Lindau tumor suppressor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

Fibronectin is a hypoxia-independent target of the tumor suppressor VHL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

The von Hippel-Lindau protein interacts with heteronuclear ribonucleoprotein a2 and regulates its expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

VHL takes HIF's breath away

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

7 January 2021

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

7 January 2021

Consequences of angiogenesis for tumor progression, metastasis and cancer therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

7 January 2021

The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700907

7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700907

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Dimensions Publication ID

19 September 2017

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