Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide (Q40415765)

20 September 2017

Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide (English)

1 reference

20 September 2017

Irfan Y Tamboli

1

1 reference

20 September 2017

Kai Prager

2

1 reference

20 September 2017

Esther Barth

3

1 reference

20 September 2017

Michael Heneka

4

1 reference

20 September 2017

Konrad Sandhoff

5

1 reference

20 September 2017

Jochen Walter

6

1 reference

20 September 2017

language of work or name

English

0 references

publication date

27 May 2005

1 reference

Journal of Biological Chemistry

20 September 2017

1 reference

20 September 2017

280

1 reference

20 September 2017

30

1 reference

20 September 2017

28110-28117

1 reference

Games played by rogue proteins in prion disorders and Alzheimer's disease

20 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

A cell biological perspective on Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

The cell biology of Alzheimer's disease: uncovering the secrets of secretases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Intramembrane proteolysis by presenilins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Cholesterol and the biology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Cholesterol, A beta and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Neuronal membrane cholesterol loss enhances amyloid peptide generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

GM1 ganglioside-bound amyloid beta-protein in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

A seed for Alzheimer amyloid in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Combinatorial ganglioside biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

How proteins move lipids and lipids move proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Functions of lipid rafts in biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Endocytosis and sorting of glycosphingolipids in sphingolipid storage disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

The glycosphingolipidoses-from disease to basic principles of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Ectodomain phosphorylation of beta-amyloid precursor protein at two distinct cellular locations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

PDMP blocks brefeldin A-induced retrograde membrane transport from golgi to ER: evidence for involvement of calcium homeostasis and dissociation from sphingolipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Identification of a beta-secretase activity, which truncates amyloid beta-peptide after its presenilin-dependent generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

A mouse B16 melanoma mutant deficient in glycolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Glycosphingolipids are required for sorting melanosomal proteins in the Golgi complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Functional expression of CD4, CXCR4, and CCR5 in glycosphingolipid-deficient mouse melanoma GM95 cells and susceptibility to HIV-1 envelope glycoprotein-triggered membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Ganglioside-dependent cell attachment and endocytosis of murine polyomavirus-like particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Role of lipids in the retrograde pathway of ricin intoxication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Specific lipid requirements of membrane proteins--a putative bottleneck in heterologous expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Modulation of amyloid precursor protein cleavage by cellular sphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Enhanced insulin sensitivity in mice lacking ganglioside GM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Intracellular transport of GPI-anchored proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Inhibition of Receptor-mediated Endocytosis Demonstrates Generation of Amyloid β-Protein at the Cell Surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

Sphingolipid Depletion Increases Formation of the Scrapie Prion Protein in Neuroblastoma Cells Infected with Prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414525200

21 January 2018

Identifiers

DOI

10.1074/JBC.M414525200

1 reference

20 September 2017

1 reference