Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis. (Q40415912)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922743%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis (English)

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12 January 2020

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2

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12 January 2020

author name string

Sunil K Halder

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922743%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Pran K Datta

series ordinal

3

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language of work or name

English

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publication date

19 April 2005

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Experimental Cell Research

12 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922743%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

307

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12 January 2020

issue

1

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12 January 2020

page(s)

231-246

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Smads as transcriptional co-modulators

12 January 2020

cites work

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TGF-beta signal transduction

7 January 2021

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Transcriptional control by the TGF-beta/Smad signaling system

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STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling

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TGF-beta signaling in tumor suppression and cancer progression

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Deficient Smad7 expression: a putative molecular defect in scleroderma

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Smad7: a new key player in TGF-beta-associated disease

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The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

7 January 2021

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Expression of Smad proteins in human colorectal cancer.

7 January 2021

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Combined copy status of 18q21 genes in colorectal cancer shows frequent retention of SMAD7

7 January 2021

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Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis

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Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

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Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

7 January 2021

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Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

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Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases

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Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

7 January 2021

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Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

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Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells

7 January 2021

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TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector

7 January 2021

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Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells

7 January 2021

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Heterogeneity of human colon carcinoma

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7 January 2021

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Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosis

7 January 2021

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Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells

7 January 2021

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Apoptosis in podocytes induced by TGF-beta and Smad7

7 January 2021

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Evidence for a role of the JNK cascade in Smad7-mediated apoptosis

7 January 2021

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7 January 2021

The Bcl-2 protein family

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Grape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathways

7 January 2021

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Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta

7 January 2021

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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

7 January 2021

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Critical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis

7 January 2021

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7 January 2021

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7 January 2021

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New functional activities for the p21 family of CDK inhibitors

7 January 2021

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

7 January 2021

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The cyclin-dependent kinase inhibitor p21WAF1/Cip1 is an antiestrogen-regulated inhibitor of Cdk4 in human breast cancer cells

7 January 2021

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10.1016/J.YEXCR.2005.03.009

7 January 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922743%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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