Essential role of p38gamma in K-Ras transformation independent of phosphorylation (Q40430785)

20 September 2017

Essential role of p38gamma in K-Ras transformation independent of phosphorylation (English)

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20 September 2017

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Jun Tang

1

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20 September 2017

Xiaomei Qi

2

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20 September 2017

Dan Mercola

3

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20 September 2017

Jiahuai Han

4

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20 September 2017

Guan Chen

5

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20 September 2017

language of work or name

English

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publication date

25 April 2005

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20 September 2017

8

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Journal of Biological Chemistry

inferred from page(s)

published in

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20 September 2017

280

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20 September 2017

25

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20 September 2017

23910-23917

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Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex

20 September 2017

1 reference

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p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor

22 September 2017

1 reference

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Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2

22 September 2017

1 reference

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Estrogen receptor inhibits c-Jun-dependent stress-induced cell death by binding and modifying c-Jun activity in human breast cancer cells

22 September 2017

1 reference

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Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms

22 September 2017

1 reference

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A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation

22 September 2017

1 reference

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Membrane-binding and activation mechanism of PTEN.

22 September 2017

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The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain

22 September 2017

1 reference

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ERK6 is expressed in a developmentally regulated manner in rodent skeletal muscle

22 September 2017

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Signal transduction. MAP kinase signaling specificity

22 September 2017

1 reference

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A system for stable expression of short interfering RNAs in mammalian cells

22 September 2017

1 reference

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MAPK-regulated transcription: a continuously variable gene switch?

22 September 2017

1 reference

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Mammalian MAP kinase signalling cascades

22 September 2017

1 reference

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TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

22 September 2017

1 reference

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Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

22 September 2017

1 reference

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p38 MAP kinases: beyond the stress response

22 September 2017

1 reference

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Elucidating cell signaling mechanisms using antisense technology

22 September 2017

1 reference

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The p38 signal transduction pathway: activation and function

22 September 2017

1 reference

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Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells

22 September 2017

1 reference

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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

22 September 2017

1 reference

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Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition

22 September 2017

1 reference

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Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy

22 September 2017

1 reference

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Hyperexpression of mitogen-activated protein kinase in human breast cancer

22 September 2017

1 reference

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Mitogen-activated protein kinase pathways

22 September 2017

1 reference

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Cellular transformation and malignancy induced by ras require c-jun

22 September 2017

1 reference

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ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation

22 September 2017

1 reference

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Proteins regulating Ras and its relatives

22 September 2017

1 reference

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Transformation of mammalian cells by constitutively active MAP kinase kinase

22 September 2017

1 reference

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

22 September 2017

1 reference

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

22 September 2017

1 reference

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

22 September 2017

1 reference

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

22 September 2017

1 reference

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Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation

22 September 2017

1 reference

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Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells

25 September 2017

1 reference

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The p38 pathway provides negative feedback for Ras proliferative signaling

25 September 2017

1 reference

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Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis

25 September 2017

1 reference

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A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

25 September 2017

1 reference

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p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity

25 September 2017

1 reference

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Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38alpha and p38delta MAPK isoforms by TGF-beta 1 in murine mesangial cells.

15 June 2018

1 reference

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Ras stimulates DNA topoisomerase II alpha through MEK: a link between oncogenic signaling and a therapeutic target

15 June 2018

1 reference

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Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor, SB203580.

15 June 2018

1 reference

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The primary structure of p38 gamma: a new member of p38 group of MAP kinases

15 June 2018

1 reference

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Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

15 June 2018

1 reference

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Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis

15 June 2018

1 reference

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20 August 2018

1 reference

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20 August 2018

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The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair

20 August 2018

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Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes

20 August 2018

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The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition

20 August 2018

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Increasing complexity of the Ras signaling pathway

20 August 2018

1 reference

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20 August 2018

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1 October 2018

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Crossref

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21 January 2018

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Crossref

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Opposing role of mitogen-activated protein kinase subtypes, erk-1/2 and p38, in the regulation of chondrogenesis of mesenchymes

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12 December 2020

Cisplatin and UV radiation induce activation of the stress-activated protein kinase p38gamma in human melanoma cells

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The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation

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Opinion: Searching for the elusive targets of farnesyltransferase inhibitors

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Identifiers

DOI

10.1074/JBC.M500699200

1 reference

20 September 2017

1 reference

20 September 2017

PubMed publication ID

15851477

1 reference