Geldanamycins exquisitely inhibit HGF/SF-mediated tumor cell invasion (Q40443951)

20 September 2017

Geldanamycins exquisitely inhibit HGF/SF-mediated tumor cell invasion (English)

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20 September 2017

Qian Xie

1

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20 September 2017

Chong-Feng Gao

2

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20 September 2017

Nariyoshi Shinomiya

3

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20 September 2017

Edward Sausville

4

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20 September 2017

Rick Hay

5

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20 September 2017

Margaret Gustafson

6

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20 September 2017

Yuehai Shen

7

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20 September 2017

David Wenkert

8

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20 September 2017

George F Vande Woude

9

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20 September 2017

language of work or name

English

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publication date

1 May 2005

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20 September 2017

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20 September 2017

24

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23

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20 September 2017

3697-3707

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208499

20 September 2017

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cites work

Met, metastasis, motility and more

1 reference

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Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs

21 January 2018

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p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2.

21 January 2018

1 reference

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Cellular receptor for urokinase-type plasminogen activator: function in cell-surface proteolysis

21 January 2018

1 reference

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Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness

21 January 2018

1 reference

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The Hsp90 chaperone complex as a novel target for cancer therapy

21 January 2018

1 reference

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Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.

21 January 2018

1 reference

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The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism

21 January 2018

1 reference

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Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network

21 January 2018

1 reference

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

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Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition

21 January 2018

1 reference

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Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

21 January 2018

1 reference

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Geldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperones

21 January 2018

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Molecular mechanisms of glioma invasiveness: the role of proteases

21 January 2018

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Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

21 January 2018

1 reference

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Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

21 January 2018

1 reference

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Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208499

Geldanamycin-induced destabilization of Raf-1 involves the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208499

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208499

Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents

21 January 2018

1 reference

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Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208499

Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation

21 January 2018

1 reference

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Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208499

Expression and localisation of urokinase-type plasminogen activator gene in gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208499

Diamine and triamine analogs and derivatives as inhibitors of deoxyhypusine synthase: synthesis and biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208499

inferred from DOI database lookup

7 January 2021

based on heuristic

Hepatocyte growth factor signaling regulates transactivation of genes belonging to the plasminogen activation system via hypoxia inducible factor-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208499

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1208499

1 reference

Dimensions Publication ID

20 September 2017

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1 reference