Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs (Q34124337)

31 July 2017

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title

Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs (English)

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31 July 2017

1

Blagosklonny MV

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PubMed ID

11960322

31 July 2017

language of work or name

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1 April 2002

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31 July 2017

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31 July 2017

16

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31 July 2017

455-462

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31 July 2017

4

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402415

31 July 2017

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Activation of the cell death program by inhibition of proteasome function

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Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition

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The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy

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7 January 2021

Targeting of the protein chaperone, HSP90, by the transformation suppressing agent, radicicol

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Geldanamycin induces cell cycle arrest in K562 erythroleukemic cells

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7 January 2021

Sequence-dependent enhancement of paclitaxel toxicity in non-small cell lung cancer by 17-allylamino 17-demethoxygeldanamycin

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7 January 2021

Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.

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7 January 2021

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

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7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

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7 January 2021

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

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7 January 2021

Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402415

7 January 2021

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

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7 January 2021

Unusual expression and localization of heat-shock proteins in human tumor cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402415

7 January 2021

Immunoconjugates of geldanamycin and anti-HER2 monoclonal antibodies: antiproliferative activity on human breast carcinoma cell lines

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402415

7 January 2021

Use of an antibody to target geldanamycin

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402415

7 January 2021

DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

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7 January 2021

Radicicol and geldanamycin prevent neurotoxic effects of anti-cancer drugs on cultured embryonic sensory neurons

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7 January 2021

Induction of hsp 72/73 by herbimycin A, an inhibitor of transformation by tyrosine kinase oncogenes.

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7 January 2021

Plasma pharmacokinetics and tissue distribution of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) in CD2F1 mice1.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402415

7 January 2021

Depletion of Raf-1 protooncogene by geldanamycin causes apoptosis in human luteinized granulosa cells

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7 January 2021

Phase I and pharmacologic study of the alkylating agent modulator novobiocin in combination with high-dose chemotherapy for the treatment of metastatic breast cancer

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7 January 2021

Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402415

7 January 2021

Don't stop for repairs in a war zone: Darwinian evolution unites genes and environment in cancer development

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402415

1 reference

PubMed ID

11960322

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

11960322