Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease. (Q40448426)

20 September 2017

Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease. (English)

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20 September 2017

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5

Peter Malfertheiner

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20 September 2017

Eike Hollenbach

1

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20 September 2017

Michael Vieth

2

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20 September 2017

Albert Roessner

3

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20 September 2017

Manfred Neumann

4

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20 September 2017

Michael Naumann

6

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20 September 2017

language of work or name

English

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publication date

3 February 2005

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

14981-14988

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20 September 2017

15

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Inflammatory Bowel Disease

20 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M500966200

Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Mucosal flora in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

NF-kappaB at the crossroads of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Activation of nuclear factor kappa B inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

NF-kappaB signaling. Many roads lead to madrid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Nods: a family of cytosolic proteins that regulate the host response to pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Genetic variation in DLG5 is associated with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Mammalian MAP kinase signalling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Regulation of the MEF2 family of transcription factors by p38

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500966200

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

The p38 mitogen-activated protein kinase regulates interleukin-1beta-induced IL-8 expression via an effect on the IL-8 promoter in intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

P38 mitogen activated protein kinase is involved in the downregulation of granulocyte CXC chemokine receptors 1 and 2 during human endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Distinct cellular functions of MK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Linkage of inflammatory bowel disease to human chromosome 6p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Review article: mitogen-activated protein kinases in chronic intestinal inflammation - targeting ancient pathways to treat modern diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

A two-step method for the extraction of high-quality RNA from endoscopic biopsies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Antibodies to interleukin 12 abrogate established experimental colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Anti-interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Innate immunity via Toll-like receptors and Nod proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

NF-kappaB: a multifaceted transcription factor regulated at several levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Cytokine gene transcription by NF-kappa B family members in patients with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Frequency of glucocorticoid resistance and dependency in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

Tumour necrosis factor α and interleukin 1β in relapse of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500966200

21 January 2018

Identifiers

DOI

10.1074/JBC.M500966200

1 reference

20 September 2017

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