Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells. (Q40459805)

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8 January 2020

title

Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells (English)

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8 January 2020

4

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8 January 2020

author name string

Kajorn Kitiphongspattana

series ordinal

1

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8 January 2020

Clayton E Mathews

series ordinal

2

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8 January 2020

Edward H Leiter

series ordinal

3

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8 January 2020

language of work or name

English

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publication date

9 February 2005

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Journal of Biological Chemistry

8 January 2020

number of pages

8

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based on heuristic

inferred from page(s)

published in

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8 January 2020

volume

280

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8 January 2020

page(s)

15727-15734

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8 January 2020

issue

16

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Significance of the rapid degradation of newly synthesized proteins in mammalian cells: a working hypothesis

8 January 2020

cites work

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

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The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control

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A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse

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Perk is essential for translational regulation and cell survival during the unfolded protein response

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

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Mutant proinsulin that cannot be converted is secreted efficiently from primary rat beta-cells via the regulated pathway

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The pathogenicity of islet-infiltrating lymphocytes in the non-obese diabetic (NOD) mouse.

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Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

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A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line

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Inhibition of proteasome activity induces concerted expression of proteasome genes and de novo formation of Mammalian proteasomes

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A simple, rapid, and sensitive DNA assay procedure

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Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation

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The growth arrest genes gas5, gas6, and CHOP-10 (gadd153) are expressed in the mouse preimplantation embryo

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Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells

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A novel quality control compartment derived from the endoplasmic reticulum

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Endoplasmic reticulum stress and the development of diabetes: a review

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Resistance of the insulin crystal to lysosomal proteases: implications for pancreatic B-cell crinophagy.

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Structural domains and molecular lifestyles of insulin and its precursors in the pancreatic beta cell

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Intracellular distribution of proteasomes

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Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

21 January 2018

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Aggresomes and Russell bodies. Symptoms of cellular indigestion?

21 January 2018

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Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway

21 January 2018

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Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

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Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity

21 January 2018

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Characterization of a mutant pancreatic eIF-2alpha kinase, PEK, and co-localization with somatostatin in islet delta cells

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21 January 2018

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21 January 2018

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Partial diversion of a mutant proinsulin (B10 aspartic acid) from the regulated to the constitutive secretory pathway in transfected AtT-20 cells

21 January 2018

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Intracellular transport and sorting of mutant human proinsulins that fail to form hexamers

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21 January 2018

Identifiers

DOI

10.1074/JBC.M410876200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15705591%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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