Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity. (Q40494340)

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4 January 2020

title

Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity (English)

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4

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author name string

Koen Brusselmans

series ordinal

1

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4 January 2020

Ruth Vrolix

series ordinal

2

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4 January 2020

Guido Verhoeven

series ordinal

3

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language of work or name

English

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publication date

8 November 2004

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Journal of Biological Chemistry

4 January 2020

published in

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volume

280

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issue

7

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page(s)

5636-5645

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Dietary flavonoids: bioavailability, metabolic effects, and safety

4 January 2020

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Epigallocatechin-3-gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells

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Fatty acid synthase, a proficient multifunctional enzyme

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Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer.

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Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

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The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung

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Synthesis and antitumor activity of an inhibitor of fatty acid synthase

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Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Androgens markedly stimulate the accumulation of neutral lipids in the human prostatic adenocarcinoma cell line LNCaP.

21 January 2018

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Inhibition of cleavage of Moloney murine leukemia virus gag and env coded precursor polyproteins by cerulenin

21 January 2018

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Effects of inhibitors of lipid synthesis on the replication of rous sarcoma virus. A specific effect of cerulenin on the processing of major non-glycosylated viral structural proteins

21 January 2018

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Inhibitory effects of flavonoids on animal fatty acid synthase

21 January 2018

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The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase

21 January 2018

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Presence of Fatty Acid Synthase Inhibitors in the Rhizome ofAlpinia officinarumHance

21 January 2018

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Absorption of kaempferol from endive, a source of kaempferol-3-glucuronide, in humans

21 January 2018

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Pharmacokinetics and bioavailability of quercetin glycosides in humans

21 January 2018

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Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue

21 January 2018

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Flavonoids increase the intracellular glutathione level by transactivation of the gamma-glutamylcysteine synthetase catalytical subunit promoter

21 January 2018

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Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I.

21 January 2018

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Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1.

21 January 2018

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21 January 2018

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Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

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Identifiers

DOI

10.1074/JBC.M408177200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15533929%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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