Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intake (Q40532834)

21 September 2017

Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intake (English)

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21 September 2017

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Keiko Hosohata

1

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21 September 2017

Daisuke Yoshioka

2

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21 September 2017

Akira Tanaka

3

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21 September 2017

Hitoshi Ando

4

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21 September 2017

Akio Fujimura

5

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21 September 2017

17 September 2015

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21 September 2017

Hypertension Research

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21 September 2017

39

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21 September 2017

19-26

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21 September 2017

1

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https://scigraph.springernature.com/pub.10.1038/hr.2015.103

21 September 2017

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Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury.

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Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury.

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Lipocalin-2 (24p3/neutrophil gelatinase-associated lipocalin (NGAL)) receptor is expressed in distal nephron and mediates protein endocytosis.

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Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats

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The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake

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Receptor-mediated endocytosis in renal proximal tubule

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Size-selectivity of the glomerular barrier to high molecular weight proteins: upper size limitations of shunt pathways

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Pathophysiology of proteinuria

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Tubulointerstitial changes as a major determinant in the progression of renal damage

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Salt loading produces severe renal hemodynamic dysfunction independent of arterial pressure in spontaneously hypertensive rats

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12 December 2020

Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury

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12 December 2020

Relationship between salt and blood pressure in hypertensive patients on chronic ACE-inhibition.

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12 December 2020

Role of tubule epithelial cells in the pathogenesis of tubulointerstitial fibrosis induced by glomerular disease

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Salt induces myocardial and renal fibrosis in normotensive and hypertensive rats

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12 December 2020

Identification of Neutrophil Gelatinase-Associated Lipocalin as a Novel Early Urinary Biomarker for Ischemic Renal Injury

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12 December 2020

Double-blind study of three sodium intakes and long-term effects of sodium restriction in essential hypertension

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12 December 2020

Pressure overload-induced transient oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin II

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12 December 2020

An in-depth examination of the excretion of albumin and other sensitive markers of renal damage in mild hypertension

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12 December 2020

Salt: blood pressure, the kidney, and other harmful effects

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12 December 2020

Dietary sodium and target organ damage in essential hypertension

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12 December 2020

Effects on left ventricular hypertrophy of long-term nonpharmacological treatment with sodium restriction in mild-to-moderate essential hypertension

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12 December 2020

Identifiers

DOI

10.1038/HR.2015.103

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Dimensions Publication ID

21 September 2017

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