Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux. (Q40558191)

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28 December 2019

title

Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux (English)

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28 December 2019

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2

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28 December 2019

Phillip K. Darcy

7

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28 December 2019

Ricky W Johnstone

8

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28 December 2019

author name string

Tainton KM

1

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28 December 2019

Jackson JT

3

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28 December 2019

Tanner JE

4

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28 December 2019

Cerruti L

5

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28 December 2019

Jane SM

6

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28 December 2019

publication date

1 September 2004

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Cell Death & Differentiation

28 December 2019

published in

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28 December 2019

volume

11

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28 December 2019

issue

9

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28 December 2019

page(s)

1028-1037

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401440

28 December 2019

exact match

0 references

cites work

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

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Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

21 January 2018

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Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

21 January 2018

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Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis

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ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

21 January 2018

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Is the multidrug transporter a flippase?

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MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

21 January 2018

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The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

21 January 2018

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Human MDR 1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts.

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Apoptosis: a link between cancer genetics and chemotherapy

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Anti-P-glycoprotein antibody-induced apoptosis of activated peripheral blood lymphocytes: a possible role of P-glycoprotein in lymphocyte survival

21 January 2018

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Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein

21 January 2018

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Is rhodamine 123 an appropriate fluorescent probe to assess P-glycoprotein mediated multidrug resistance in vinblastine-resistant CHO cells?

21 January 2018

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Antimitotic peptides and depsipeptides

21 January 2018

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The effect of antimicrotubule agents on signal transduction pathways of apoptosis: a review

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Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody

21 January 2018

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

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Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines

21 January 2018

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P-glycoprotein Does Not Protect Cells against Cytolysis Induced by Pore-forming Proteins

21 January 2018

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Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance

21 January 2018

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Multiple physiological functions for multidrug transporter P-glycoprotein?

21 January 2018

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P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation.

21 January 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

21 January 2018

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Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells

21 January 2018

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The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

21 January 2018

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

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A novel method for direct and fluorescence independent determination of drug efflux out of leukemic blast cells

21 January 2018

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Equivalent Death of P-Glycoprotein Expressing and Nonexpressing Cells Induced by the Protein Kinase C Inhibitor Staurosporine

21 January 2018

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Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process

21 January 2018

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ATPase activity of partially purified P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Resistance to spontaneous apoptosis in acute myeloid leukaemia blasts is associated with p-glycoprotein expression and function, but not with the presence of FLT3 internal tandem duplications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401440

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CDD.4401440

1 reference

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Dimensions Publication ID

28 December 2019

0 references

1 reference