Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior (Q40565424)

21 September 2017

Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior (English)

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21 September 2017

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1

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Johan Vallon-Christersson

21 September 2017

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21 September 2017

Linda Holmquist

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21 September 2017

Håkan Axelson

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21 September 2017

Ake Borg

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21 September 2017

Sven Påhlman

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21 September 2017

language of work or name

English

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publication date

1 May 2004

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Experimental Cell Research

21 September 2017

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21 September 2017

295

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2

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21 September 2017

469-487

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Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies

21 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data.

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

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N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant.

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

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1 reference

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DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation

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1 reference

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High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type

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1 reference

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Mitogenic response of human SH-SY5Y neuroblastoma cells to insulin-like growth factor I and II is dependent on the stage of differentiation

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Acute hypoxia increases the aggressive characteristics and survival properties of prostate cancer cells

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1 reference

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Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha

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1 reference

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

Evidence for hypoxia-induced neuronal-to-chromaffin metaplasia in neuroblastoma.

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

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Hypoxia-induced VEGF enhances tumor survivability via suppression of serum deprivation-induced apoptosis

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

Hypoxia induces hexokinase II gene expression in human lung cell line A549.

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

Notch signaling induces rapid degradation of achaete-scute homolog 1.

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.01.013

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7 January 2021

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DOI

10.1016/J.YEXCR.2004.01.013

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21 September 2017

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