Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation (Q40590054)

21 September 2017

Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation (English)

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21 September 2017

John H Kehrl

2

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author name string

Chong-Shan Shi

series ordinal

1

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PubMed ID

14963038

21 September 2017

language of work or name

English

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publication date

12 February 2004

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Journal of Biological Chemistry

21 September 2017

8

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based on heuristic

inferred from page(s)

published in

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21 September 2017

279

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21 September 2017

17

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21 September 2017

17224-17231

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Gp130 and the interleukin-6 family of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Interleukin 2 signaling involves the phosphorylation of Stat proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of cytokines on sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

STAT proteins: From normal control of cellular events to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Requirement of Ca(2+) and PKCdelta for Janus kinase 2 activation by angiotensin II: involvement of PYK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Regulation of angiotensin II-induced phosphorylation of STAT3 in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Signaling through focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

RAFTK/Pyk2-mediated cellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Protection from natural killer cell-mediated lysis by HLA-G expression on target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Mutational analysis of acute-phase response factor/Stat3 activation and dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

STAT3 mediates the survival signal in oncogenic ras-transfected intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

STAT3 is required for the gp130-mediated full activation of the c-myc gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Regulation of Stat3 activation by MEK kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Regulation of STAT3 by direct binding to the Rac1 GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Angiotensin II initiates tyrosine kinase Pyk2-dependent signalings leading to activation of Rac1-mediated c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Regulation of erythropoietin-induced STAT serine phosphorylation by distinct mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Regulation of STAT3 activity by G16-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Janus Kinase 2 Activation by the Platelet-Activating Factor Receptor (PAFR): Roles of Tyk2 and PAFR C Terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311875200

21 January 2018

Identifiers

DOI

10.1074/JBC.M311875200

1 reference

21 September 2017

1 reference

PubMed ID

14963038