The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation (Q40624316)

22 September 2017

The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation (English)

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22 September 2017

2

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22 September 2017

Anna N Moraitis

1

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PubMed ID

14570920

22 September 2017

language of work or name

English

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publication date

21 October 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

52

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22 September 2017

52511-52518

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The 26S proteasome: a molecular machine designed for controlled proteolysis

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

How the ubiquitin-proteasome system controls transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Importance of the regulation of nuclear receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Hormone-dependent changes in A and B forms of progesterone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Proteasomal regulation of nuclear receptor corepressor-mediated repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Human estrogen receptor-alpha: regulation by synthesis, modification and degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Disruption of the nuclear hormone receptor RORalpha in staggerer mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Orphan nuclear receptor ROR alpha-deficient mice display the cerebellar defects of staggerer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

staggerer phenotype in retinoid-related orphan receptor alpha-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Novel mechanism of nuclear receptor corepressor interaction dictated by activation function 2 helix determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Coactivators for the Orphan Nuclear Receptor ROR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Differential regulation of the N-myc proto-oncogene by ROR alpha and RVR, two orphan members of the superfamily of nuclear hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Determinants of target gene specificity for ROR alpha 1: monomeric DNA binding by an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Proteasome inhibitors: valuable new tools for cell biologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

PEST sequences and regulation by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Emerging roles of ubiquitin in transcription regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Regulation of transcriptional activation domain function by ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Transcription. Proteasome parts at gene promoters

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M308152200

Recruitment of a 19S proteasome subcomplex to an activated promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

GAL4 interacts with TATA-binding protein and coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

The Gal4 activation domain binds Sug2 protein, a proteasome component, in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Transcriptional Activation and Repression by ROR , an Orphan Nuclear Receptor Required for Cerebellar Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

9-cis-retinoic acid decreases the level of its cognate receptor, retinoid X receptor, through acceleration of the turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

ATPase and ubiquitin-binding proteins of the yeast proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308152200

21 January 2018

Identifiers

DOI

10.1074/JBC.M308152200

1 reference

22 September 2017

1 reference

PubMed ID

14570920