Bmi-1 Regulation of INK4A-ARF Is a Downstream Requirement for Transformation of Hematopoietic Progenitors by E2a-Pbx1 (Q40627636)

22 September 2017

Bmi-1 Regulation of INK4A-ARF Is a Downstream Requirement for Transformation of Hematopoietic Progenitors by E2a-Pbx1 (English)

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https://api.crossref.org/works/10.1016/S1097-2765(03)00277-6

19 March 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14536079

regulation of gene expression

19 March 2024

1 reference

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19 March 2024

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19 March 2024

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Douglas T Ross

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22 September 2017

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David Botstein

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22 September 2017

Merel Lingbeek

3

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22 September 2017

Maarten van Lohuizen

6

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22 September 2017

Kevin S. Smith

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14536079

19 March 2024

Sumit K. Chanda

2

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19 March 2024

Michael L. Cleary

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19 March 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14536079

19 March 2024

publication date

1 August 2003

1 reference

full work available at URL

22 September 2017

http://www.cell.com/article/S1097276503002776/pdf

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14536079

https://api.elsevier.com/content/article/PII:S1097276503002776?httpAccept=text/xml

19 March 2024

1 reference

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https://api.elsevier.com/content/article/PII:S1097276503002776?httpAccept=text/plain

19 March 2024

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https://api.crossref.org/works/10.1016/S1097-2765(03)00277-6

19 March 2024

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22 September 2017

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22 September 2017

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22 September 2017

393-400

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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

The INK4a/ARF tumor suppressor: one gene--two products--two pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Transformation by the Bmi-1 oncoprotein correlates with its subnuclear localization but not its transcriptional suppression activity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Exploring the metabolic and genetic control of gene expression on a genomic scale

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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Cluster analysis and display of genome-wide expression patterns

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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Splicing into senescence: the curious case of p16 and p19ARF.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

The transcriptional program in the response of human fibroblasts to serum

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Different patterns of homozygous p16INK4A and p15INK4B deletions in childhood acute lymphoblastic leukemias containing distinct E2A translocations

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Hox proteins meet more partners

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Production of high-titer helper-free retroviruses by transient transfection

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

CD19, the earliest differentiation antigen of the B cell lineage, bears three extracellular immunoglobulin-like domains and an Epstein-Barr virus-related cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900277-6

7 January 2021

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

18

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(03)00277-6

Homozygous deletions of p16/MTS1 and p15/MTS2 genes are frequent in t(1;19)-negative but not in t(1;19)-positive B precursor acute lymphoblastic leukemia in childhood

19 March 2024

35

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https://api.crossref.org/works/10.1016/S1097-2765(03)00277-6

19 March 2024

Identifiers

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22 September 2017

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