Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria (Q40644298)

22 September 2017

Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria (English)

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22 September 2017

Xu Dong Zhang

1

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22 September 2017

Jodie M Borrow

2

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22 September 2017

Xi Yi Zhang

3

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22 September 2017

Tam Nguyen

4

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22 September 2017

Peter Hersey

5

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22 September 2017

language of work or name

English

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publication date

1 May 2003

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22 September 2017

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22 September 2017

22

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22 September 2017

19

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22 September 2017

2869-2881

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206427

22 September 2017

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Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

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MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors

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The Bcl-2 protein family: arbiters of cell survival

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7 January 2021

Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

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7 January 2021

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

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7 January 2021

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

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7 January 2021

TRAIL: a molecule with multiple receptors and control mechanisms

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7 January 2021

The CARD domain: a new apoptotic signalling motif

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Inhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis

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Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

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7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

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7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

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7 January 2021

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7 January 2021

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

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7 January 2021

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

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7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

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Identification and characterization of a new member of the TNF family that induces apoptosis

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206427

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Dimensions Publication ID

22 September 2017

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1 reference