Multiple domains of the mouse p19ARF tumor suppressor are involved in p53-independent apoptosis (Q40670279)

22 September 2017

Multiple domains of the mouse p19ARF tumor suppressor are involved in p53-independent apoptosis (English)

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22 September 2017

1

Masaaki Matsuoka

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22 September 2017

Megumi Kurita

2

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22 September 2017

Haruka Sudo

3

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22 September 2017

Kiyohisa Mizumoto

4

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22 September 2017

Ikuo Nishimoto

5

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22 September 2017

Etsuro Ogata

6

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22 September 2017

1 February 2003

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Biochemical and Biophysical Research Communications

22 September 2017

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22 September 2017

301

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22 September 2017

1000-1010

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22 September 2017

4

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Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

p14ARF links the tumour suppressors RB and p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

E1A signaling to p53 involves the p19(ARF) tumor suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

p19ARF links the tumour suppressor p53 to Ras

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Aberrations of the p53 pathway components p53, MDM2 and CDKN2A appear independent in diffuse large B cell lymphoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

p53-independent functions of the p19(ARF) tumor suppressor

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

p53-independent apoptosis is induced by the p19ARF tumor suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Differential effect of ik3-1/cables on p53- and p73-induced cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Sensitivity and reproducibility in adenoviral infectious titer determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Identification of ionizable groups essential for the enzyme catalysis on glutathione S-transferase P.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

ik3-2, a relative to ik3-1/cables, is associated with cdk3, cdk5, and c-abl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Induction of apoptosis and G2/M arrest by infection with replication-deficient adenovirus at high multiplicity of infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

A major functional difference between the mouse and human ARF tumor suppressor proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Role of the INK4a locus in tumor suppression and cell mortality.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

The INK4A/ARF locus and its two gene products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900080-9

10.1016/S0006-291X(03)00080-9

7 January 2021

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DOI

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22 September 2017

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