Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity (Q40701329)

22 September 2017

Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity (English)

1 reference

22 September 2017

Magnus Ingelman-Sundberg

8

object named as

Magnus Ingelman-Sundberg

0 references

Mikael Oscarson

1

object named as

Mikael Oscarson

1 reference

22 September 2017

Roman A McLellan

2

1 reference

22 September 2017

Vendela Asp

3

1 reference

22 September 2017

MariCarmen Ledesma

4

1 reference

22 September 2017

Maria Luisa Bernal Ruiz

5

1 reference

22 September 2017

Blanca Sinues

6

1 reference

22 September 2017

Arja Rautio

7

1 reference

22 September 2017

1 October 2002

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22 September 2017

1 reference

22 September 2017

20

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22 September 2017

4

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22 September 2017

275-283

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The role of individual human cytochromes P450 in drug metabolism and clinical response

22 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Identification of a 43-kDa protein in human liver cytosol that binds to the 3'-untranslated region of CYP2A6 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Duplication, multiduplication, and amplification of genes encoding drug-metabolizing enzymes: evolutionary, toxicological, and clinical pharmacological aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Human cytochrome P450 (CYP) genes: recommendations for the nomenclature of alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

CYP2A6*6, a novel polymorphism in cytochrome p450 2A6, has a single amino acid substitution (R128Q) that inactivates enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Expression of CYP2A genes in human liver and extrahepatic tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Microsomal p450s use specific proline-rich sequences for efficient folding, but not for maintenance of the folded structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Nicotine metabolism and CYP2A6 allele frequencies in Koreans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Relationship between interindividual differences in nicotine metabolism and CYP2A6 genetic polymorphism in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Hepatitis A impairs the function of human hepatic CYP2A6 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

CYP2A6: a human coumarin 7-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: impairment of its promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Polymorphisms of CYP2A6 and its practical consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

Variability of coumarin 7- and 3-hydroxylation in a Jordanian population is suggestive of a functional polymorphism in cytochrome P450 CYP2A6

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

7 January 2021

Interindividual variability of coumarin 7-hydroxylation in a Turkish population

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

7 January 2021

CYP2A6 gene deletion reduces susceptibility to lung cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

7 January 2021

A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502).

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

7 January 2021

Characterisation and PCR-based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

7 January 2021

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.10126

7 January 2021

Identifiers

DOI

10.1002/HUMU.10126

1 reference

22 September 2017

1 reference