Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase (Q40709028)

23 September 2017

Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase (English)

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23 September 2017

1

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author name string

Cole M Zimmerman

series ordinal

2

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PubMed ID

12193595

23 September 2017

Lawrence S Mathews

series ordinal

3

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PubMed ID

12193595

23 September 2017

language of work or name

English

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publication date

21 August 2002

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

44

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23 September 2017

41361-41368

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Regulation of Smad signalling by protein associations and signalling crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Smads as transcriptional co-modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Smad proteins physically interact with calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Calmodulin differentially modulates Smad1 and Smad2 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Involvement of p21ras in Xenopus mesoderm induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Isolation and characterization of a novel dual specific phosphatase, HVH2, which selectively dephosphorylates the mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

A transcriptional partner for MAD proteins in TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Characterization of type I receptors for transforming growth factor-beta and activin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Ca2+-induced hydrophobic site on calmodulin: application for purification of calmodulin by phenyl-Sepharose affinity chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Regulation of activin type I receptor function by phosphorylation of residues outside the GS domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Smad4 and FAST-1 in the assembly of activin-responsive factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

From receptors to stress-activated MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Smads and early developmental signaling by the TGFbeta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

The Spemann organizer-expressed zinc finger gene Xegr-1 responds to the MAP kinase/Ets-SRF signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Metastasis is driven by sequential elevation of H-ras and Smad2 levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Increasing complexity of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Ras enhances Myc protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204597200

21 January 2018

Identifiers

DOI

10.1074/JBC.M204597200

1 reference

23 September 2017

1 reference

PubMed ID

12193595