PARP-1 modifies the effectiveness of p53-mediated DNA damage response. (Q40750146)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11850828%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

PARP-1 modifies the effectiveness of p53-mediated DNA damage response (English)

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7 December 2019

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Mariano Ruíz de Almodovar

4

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7 December 2019

author name string

M Teresa Valenzuela

1

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7 December 2019

Rosario Guerrero

2

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7 December 2019

M Isabel Núñez

3

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7 December 2019

Malabika Sarker

5

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7 December 2019

Gilbert de Murcia

6

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7 December 2019

F Javier Oliver

7

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7 December 2019

language of work or name

English

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publication date

1 February 2002

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7 December 2019

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7 December 2019

volume

21

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7 December 2019

issue

7

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7 December 2019

page(s)

1108-1116

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205169

7 December 2019

exact match

0 references

cites work

Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase

1 reference

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

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DNA excision repair and DNA damage-induced apoptosis are linked to Poly(ADP-ribosyl)ation but have different requirements for p53

21 January 2018

1 reference

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Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

21 January 2018

1 reference

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

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Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells.

21 January 2018

1 reference

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Involvement of poly(ADP-ribose) polymerase in base excision repair

21 January 2018

1 reference

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Poly(ADP-ribose) polymerase: a molecular nick-sensor

21 January 2018

1 reference

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Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

21 January 2018

1 reference

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Poly(ADP-ribose) polymerase, a major determinant of early cell response to ionizing radiation

21 January 2018

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ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

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Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

21 January 2018

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Regulation of p53 in response to DNA damage

21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

1 reference

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Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions

21 January 2018

1 reference

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XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

21 January 2018

1 reference

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Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

21 January 2018

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Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

21 January 2018

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ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

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Poly(ADP-ribose) polymerase in the cellular response to DNA damage, apoptosis, and disease

21 January 2018

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Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

21 January 2018

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Initial radiation-induced DNA damage in human tumour cell lines: a correlation with intrinsic cellular radiosensitivity.

21 January 2018

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4-Amino-1,8-naphthalimide: a novel inhibitor of poly(ADP-ribose) polymerase and radiation sensitizer

21 January 2018

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A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

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DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines

21 January 2018

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A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

21 January 2018

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Lethal and potentially lethal lesions induced by radiation--a unified repair model

21 January 2018

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7 January 2021

DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

1 reference

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7 January 2021

Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion

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7 January 2021

Poly(ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation

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7 January 2021

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11850828%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 December 2019

0 references

1 reference