PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway. (Q40755882)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11803475%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway (English)

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6 December 2019

2

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6 December 2019

author name string

Xiu-Juan Yuan

series ordinal

1

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6 December 2019

language of work or name

English

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publication date

1 January 2002

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6 December 2019

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6 December 2019

volume

21

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6 December 2019

issue

2

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6 December 2019

page(s)

319-327

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Apoptosis control by death and decoy receptors

6 December 2019

cites work

1 reference

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The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

21 January 2018

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Biochemical pathways of caspase activation during apoptosis

21 January 2018

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Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

21 January 2018

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Lipopolysaccharide mediates endothelial apoptosis by a FADD-dependent pathway

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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Pten is essential for embryonic development and tumour suppression

21 January 2018

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis

21 January 2018

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A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line

21 January 2018

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A simplified system for generating recombinant adenoviruses

21 January 2018

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Cell cycle arrest by the PTEN tumor suppressor is target cell specific and may require protein phosphatase activity

21 January 2018

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Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

21 January 2018

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

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Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

21 January 2018

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The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

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P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

21 January 2018

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Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis

21 January 2018

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A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

21 January 2018

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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

21 January 2018

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Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis

21 January 2018

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Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

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FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

21 January 2018

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Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells

21 January 2018

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Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

21 January 2018

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

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Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism

21 January 2018

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Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance

21 January 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model

21 January 2018

1 reference

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Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

21 January 2018

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The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

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FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

21 January 2018

1 reference

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High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1205054

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