Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein. (Q40790692)

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9 November 2019

title

Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein (English)

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9 November 2019

3

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9 November 2019

author name string

K E Keating

1

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9 November 2019

N Gueven

2

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9 November 2019

H P Rodemann

4

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9 November 2019

M F Lavin

5

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9 November 2019

language of work or name

English

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publication date

1 July 2001

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9 November 2019

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9 November 2019

volume

20

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9 November 2019

page(s)

4281-4290

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9 November 2019

issue

32

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204527

9 November 2019

exact match

0 references

cites work

Growth factors and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

The effect of ionizing radiation on signal transduction: antibodies to EGF receptor sensitize A431 cells to radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Receptors for epidermal growth factor and other polypeptide mitogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Upregulation of ATM in sclerosing adenosis of the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

ATM-dependent phosphorylation of nibrin in response to radiation exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Predominance of null mutations in ataxia-telangiectasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Identification and characterization of a new gene physically linked to the ATM gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Epidermal growth factor reduces resistance to doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

The genetic defect in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

ATM binds to beta-adaptin in cytoplasmic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Possible control of cell death pathways in ataxia telangiectasia. A case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Epidermal growth factor and okadaic acid stimulate Sp1 proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Growth-inhibitory and growth-stimulatory effects of epidermal growth factor on human breast cancer cell line, MDA.MB.436: dependence on culture conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Defective potassium currents in ataxia telangiectasia fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

ATM: from gene to function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Mouse cdc21 only 0.5 kb upstream from dna-pkcs in a head-to-head organization: an implication of co-evolution of ATM family members and cell cycle regulating genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

DNA damage activates p53 through a phosphorylation-acetylation cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

The response of ataxia-telangiectasia homozygous and heterozygous skin fibroblasts to neocarzinostatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Localization of a portion of extranuclear ATM to peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Dual roles of ATM in the cellular response to radiation and in cell growth control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

On the nature of a defect in cells from individuals with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

Growth of cultured cells from patients with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

Ataxia telangiectasia. Neoplasia, untoward response to x-irradiation, and tuberous sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

Defective calcium-dependent signal transduction in T lymphocytes of ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

Cell cycle dependence of epidermal growth factor induced radiosensitization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

Mitogen receptor redistribution defects and concomitant absence of blastogenesis in ataxia-telangiectasia T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

Effect of epidermal growth factor on the growth and radiation sensitivity of human breast cancer cells in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204527

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204527

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11466608%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 November 2019

1039995828

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Fatcat ID

release_wwozftx34bf6bpmf2s3gfqxi34

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Fatcat

https://api.fatcat.wiki/v0/release/wwozftx34bf6bpmf2s3gfqxi34

24 November 2022

mapped directly with Wikidata item

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