Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme (Q40808050)

23 September 2017

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme (English)

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23 September 2017

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E A Eckman

1

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23 September 2017

D K Reed

series ordinal

2

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23 September 2017

C B Eckman

series ordinal

3

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23 September 2017

language of work or name

English

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publication date

3 May 2001

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

276

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23 September 2017

27

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23 September 2017

24540-24548

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Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Degradation of amyloid beta-protein by a serine protease-alpha2-macroglobulin complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Molecular pharmacology of endothelin converting enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Novel activity of endothelin-converting enzyme: hydrolysis of bradykinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Hydrolysis of peptide hormones by endothelin-converting enzyme-1. A comparison with neprilysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Cellular distribution of endothelin-converting enzyme-1 in human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Organization of the gene encoding the human endothelin-converting enzyme (ECE-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Identification and characterization of two isoforms of an endothelin-converting enzyme-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Molecular characterization of human and bovine endothelin converting enzyme (ECE-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Human endothelin-converting enzyme (ECE-1): three isoforms with distinct subcellular localizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter molecular cloning and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Recombinant human endothelin-converting enzyme ECE-1b is located in an intracellular compartment when expressed in polarized Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Evidence for intracellular endothelin-converting enzyme-2 expression in cultured human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Purification of a novel endothelin-converting enzyme specific for big endothelin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Soluble human endothelin-converting enzyme-1: expression, purification, and demonstration of pronounced pH sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Peptidyl dipeptidase A: angiotensin I-converting enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Characterization of endopeptidase 3.4.24.11 ("enkephalinase") activity in human plasma and cerebrospinal fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Molecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Neutral endopeptidase-24.11 inhibitors: from analgesics to antihypertensives?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Purification of human lung angiotensin-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

A permanent human cell line (EA.hy926) preserves the characteristics of endothelin converting enzyme from primary human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Alpha-human atrial natriuretic peptide, carperitide, reduces infarct size but not arrhythmias after coronary occlusion/reperfusion in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

A live-cell assay for studying extracellular and intracellular endothelin-converting enzyme activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Phosphoramidon inhibits the intracellular conversion of big endothelin-1 to endothelin-1 in cultured endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

Cerebrospinal fluid endothelin-1 in Alzheimer's disease and senile dementia of Alzheimer type

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

The endothelin system and its potential as a therapeutic target in cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

A full genome scan for late onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007579200

21 January 2018

Identifiers

DOI

10.1074/JBC.M007579200

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23 September 2017

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