p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells (Q40810981)

23 September 2017

p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells (English)

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23 September 2017

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7

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23 September 2017

6

Scheurich P

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23 September 2017

Bartke T

1

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23 September 2017

Siegmund D

2

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23 September 2017

Peters N

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23 September 2017

Reichwein M

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23 September 2017

Henkler F

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23 September 2017

language of work or name

English

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publication date

1 February 2001

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23 September 2017

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23 September 2017

20

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23 September 2017

5

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23 September 2017

571-580

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204124

23 September 2017

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

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Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

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p53, the cellular gatekeeper for growth and division

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Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop

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Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

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Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

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Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.

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Casper is a FADD- and caspase-related inducer of apoptosis

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p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein

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FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

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Induction of p53 in the glutamate-induced cell death program

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

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Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

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Identification and classification of p53-regulated genes

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NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

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Role of NF-κB in p53-mediated programmed cell death

21 January 2018

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Additive effect between NF-kappaB subunits and p53 protein for transcriptional activation of human p53 promoter

21 January 2018

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo

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7 January 2021

Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204124

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Dimensions Publication ID

23 September 2017

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