Tel induces a G1 arrest and suppresses Ras-induced transformation (Q40842655)

24 September 2017

Tel induces a G1 arrest and suppresses Ras-induced transformation (English)

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24 September 2017

Rompaey LV

1

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24 September 2017

Potter M

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2

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24 September 2017

Adams C

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3

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24 September 2017

Grosveld G

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4

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24 September 2017

language of work or name

English

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publication date

1 November 2000

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24 September 2017

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24 September 2017

19

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24 September 2017

46

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24 September 2017

5244-5250

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203899

24 September 2017

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cites work

A physical, transcript, and deletion map of chromosome region 12p12.3 flanked by ETV6 and CDKN1B: hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

The leukemia-associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Elevated expression of Ets2 or distinct portions of Ets2 can reverse Ras-mediated cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

The ets family member Tel binds to the Fli-1 oncoprotein and inhibits its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

TEL is a sequence-specific transcriptional repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

The TEL gene products: nuclear phosphoproteins with DNA binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Increased cell-substrate adhesion accompanies conditional reversion to the normal phenotype in ras-oncogene-transformed NIH-3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Tel, a frequent target of leukemic translocations, induces cellular aggregation and influences expression of extracellular matrix components.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

Specificity within the ets family of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

7 January 2021

Characterization of 12p molecular events outside ETV6 in complex karyotypes of acute myeloid malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

7 January 2021

The Tel-PDGFRbeta fusion gene produces a chronic myeloproliferative syndrome in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

7 January 2021

ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

7 January 2021

TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

7 January 2021

The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberration in different hematological malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203899

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203899

1 reference

Dimensions Publication ID

24 September 2017

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1 reference