c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells (Q40878189)

24 September 2017

c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells (English)

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24 September 2017

6

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24 September 2017

Ceballos E

1

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24 September 2017

Delgado MD

2

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24 September 2017

Gutierrez P

3

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24 September 2017

Richard C

4

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24 September 2017

Müller D

5

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24 September 2017

Ehinger M

7

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24 September 2017

Gullberg U

8

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24 September 2017

León J

9

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24 September 2017

language of work or name

English

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publication date

1 April 2000

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24 September 2017

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24 September 2017

19

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24 September 2017

18

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24 September 2017

2194-2204

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203541

24 September 2017

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Max and inhibitory c-Myc mutants induce erythroid differentiation and resistance to apoptosis in human myeloid leukemia cells

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Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta

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Apoptosis-prone phenotype of human colon carcinoma cells with a high level amplification of the c-myc gene

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Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

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Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain

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Mediation of c-Myc-induced apoptosis by p53.

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Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

21 January 2018

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Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kappaB and Myc/Max

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p53: puzzle and paradigm

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Mutational inactivation of the p53 gene in the human erythroid leukemic K562 cell line

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Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes

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Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

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Use of retroviral vectors for gene transfer and expression

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Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135.

21 January 2018

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Wild-type murine p53 represses transcription from the murine c-myc promoter in a human glial cell line

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The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

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Genetic determinants of p53-induced apoptosis and growth arrest

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Studies of proto-oncogene expression in the chronic and blastic phases of chronic myelogenous leukemia.

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Transactivation of the human p53 tumor suppressor gene by c-Myc/Max contributes to elevated mutant p53 expression in some tumors.

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p53 mediates apoptosis induced by c-Myc activation in hypoxic or gamma irradiated fibroblasts

21 January 2018

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The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells

21 January 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

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p53 loss and point mutations are associated with suppression of apoptosis and progression of CML into myeloid blastic crisis.

21 January 2018

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The many roles of c-Myc in apoptosis

21 January 2018

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C-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent

21 January 2018

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Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

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Roles of the tumor suppressor p53 and the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in receptor-mediated apoptosis of WEHI 231 B lymphoma cells

21 January 2018

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C-myc overexpression and p53 loss cooperate to promote genomic instability

21 January 2018

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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

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Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress

21 January 2018

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7 January 2021

Changes in oncogene expression implicated in evolution of chronic granulocytic leukemia from its chronic phase to acceleration

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7 January 2021

H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism

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7 January 2021

p53 in growth control and neoplasia

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7 January 2021

Signaling through the antigen receptor of B lymphocytes activates a p53-independent pathway of c-Myc-induced apoptosis

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Bcl-2 and c-myc expression, cell cycle kinetics and apoptosis during the progression of chronic myelogenous leukemia from diagnosis to blastic phase

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7 January 2021

The proto-oncogene c-myc and apoptosis

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Traps to catch unwary oncogenes

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c-myc locus amplification and the acquisition of trisomy 8 in the evolution of chronic myeloid leukaemia

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7 January 2021

Tumor-suppressor p53: implications for tumor development and prognosis

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7 January 2021

Molecular alterations in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia

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7 January 2021

Mutant p53 can provoke apoptosis in p53-deficient Hep3B cells with delayed kinetics relative to wild-type p53

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7 January 2021

A new look at the role of p53 in leukemia cell sensitivity to chemotherapy

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7 January 2021

Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203541

1 reference

Dimensions Publication ID

24 September 2017

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1 reference