Cyclin A is a functional target of retinoblastoma tumor suppressor protein-mediated cell cycle arrest (Q40928826)

24 September 2017

title

Cyclin A is a functional target of retinoblastoma tumor suppressor protein-mediated cell cycle arrest (English)

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24 September 2017

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Knudsen KE

1

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24 September 2017

Fribourg AF

2

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24 September 2017

Strobeck MW

3

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24 September 2017

Blanchard JM

4

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24 September 2017

Knudsen ES

5

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24 September 2017

language of work or name

English

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publication date

1 September 1999

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

274

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24 September 2017

issue

39

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24 September 2017

page(s)

27632-27641

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Alterations in G1/S cell-cycle control contributing to carcinogenesis

24 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

The retinoblastoma protein pathway in cell cycle control and cancer

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Role of the Rb/E2F pathway in cell growth control

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Regulation of transcription by the retinoblastoma protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Identification of a growth suppression domain within the retinoblastoma gene product

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Control of pRB phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

21 January 2018

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Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

21 January 2018

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Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression

21 January 2018

1 reference

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Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

21 January 2018

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Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

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21 January 2018

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Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

21 January 2018

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Growth suppression by p16ink4 requires functional retinoblastoma protein

21 January 2018

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Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

21 January 2018

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Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

21 January 2018

1 reference

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Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering

21 January 2018

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The regulation of E2F by pRB-family proteins

21 January 2018

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Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

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Retinoblastoma protein recruits histone deacetylase to repress transcription

21 January 2018

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A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

21 January 2018

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Regulation of the cyclin E gene by transcription factor E2F1

21 January 2018

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Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

21 January 2018

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pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

21 January 2018

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Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Growth suppression by an E2F-binding-defective retinoblastoma protein (RB): contribution from the RB C pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Down-regulation of the cyclin A promoter in differentiating human embryonal carcinoma cells is mediated by depletion of ATF-1 and ATF-2 in the complex at the ATF/CRE site

21 January 2018

1 reference

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High-efficiency transformation of mammalian cells by plasmid DNA

21 January 2018

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Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells

21 January 2018

1 reference

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Hyperphosphorylated p107 and p130 bind to T-antigen: identification of a critical regulatory sequence present in RB but not in p107/p130.

21 January 2018

1 reference

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Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Cyclin A is required in S phase in normal epithelial cells.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Cyclin A expression is under negative transcriptional control during the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

CDF-1, a novel E2F-unrelated factor, interacts with cell cycle-regulated repressor elements in multiple promoters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

CDF-1-mediated repression of cell cycle genes targets a specific subset of transactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

p27KIP1 blocks cyclin E-dependent transactivation of cyclin A gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.39.27632

21 January 2018

Identifiers

DOI

10.1074/JBC.274.39.27632

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24 September 2017

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