neurofibromin 2 (Q410233)

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mammalian protein found in Homo sapiens
  • merlin
  • NF2
  • moesin-ezrin-radixin like
  • Neurofibromin-2
  • neurofibromin 2 (bilateral acoustic neuroma)
  • schwannomin
  • moesin-ezrin-radixin-like protein
  • schwannomerlin
  • moesin-ezrin-radizin-like protein
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Language Label Description Also known as
English
neurofibromin 2
mammalian protein found in Homo sapiens
  • merlin
  • NF2
  • moesin-ezrin-radixin like
  • Neurofibromin-2
  • neurofibromin 2 (bilateral acoustic neuroma)
  • schwannomin
  • moesin-ezrin-radixin-like protein
  • schwannomerlin
  • moesin-ezrin-radizin-like protein

Statements

molecular function
protein binding
determination method
IPI
19 references
retrieved
8 April 2019
stated in
Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin
GOA
curator
UniProt
UniProt protein ID
P35240
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands
GOA
curator
UniProt
UniProt protein ID
P35240
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Moesin-ezrin-radixin-like protein (merlin) mediates protein interacting with the carboxyl terminus-1 (PICT-1)-induced growth inhibition of glioblastoma cells in the nucleus
GOA
curator
UniProt
UniProt protein ID
P35240
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway
GOA
curator
UniProt
UniProt protein ID
P35240
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus
GOA
curator
UniProt
UniProt protein ID
P35240
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Defining the human deubiquitinating enzyme interaction landscape
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Neurofibromatosis 2 tumour suppressor schwannomin interacts with betaII-spectrin
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
retrieved
8 April 2019
stated in
The neurofibromatosis 2 tumor suppressor protein interacts with hepatocyte growth factor-regulated tyrosine kinase substrate
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35240
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE NF2 204991 s at fs.png
732 × 530; 12 KB
0 references

Identifiers

MeSH descriptor ID
D025581
subject named as
Neurofibromin 2
0 references
 
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