Liver-directed gene transfer and application to therapy (Q41063915)

26 September 2017

1 reference

title

Liver-directed gene transfer and application to therapy (English)

1 reference

26 September 2017

V Sandig

1

1 reference

PubMed ID

8740651

26 September 2017

M Strauss

series ordinal

2

1 reference

26 September 2017

1 April 1996

1 reference

Journal of Molecular Medicine

26 September 2017

1 reference

26 September 2017

74

1 reference

26 September 2017

4

1 reference

26 September 2017

205-212

1 reference

Gene transfer into hepatocytes and human liver tissue by baculovirus vectors

26 September 2017

1 reference

12 December 2020

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

1 reference

12 December 2020

Construction of an EBNA-producing line of well-differentiated human hepatoma cells and of appropriate Epstein-Barr virus-based shuttle vectors

1 reference

12 December 2020

Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses

1 reference

12 December 2020

A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes

1 reference

12 December 2020

Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo

1 reference

12 December 2020

Evaluation of Relative Promoter Strength in Primary Hepatocytes Using Optimized Lipofection

1 reference

12 December 2020

Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake

1 reference

12 December 2020

Transplantation of genetically modified autologous hepatocytes into nonhuman primates: feasibility and short-term toxicity.

1 reference

12 December 2020

Adenovirus-mediated correction of the genetic defect in hepatocytes from patients with familial hypercholesterolemia

1 reference

12 December 2020

Combination gene therapy for liver metastasis of colon carcinoma in vivo

1 reference

12 December 2020

In vivo gene therapy of hemophilia B: sustained partial correction in factor IX-deficient dogs

1 reference

12 December 2020

Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

1 reference

12 December 2020

Condensation of vector DNA by the chromosomal protein HMG1 results in efficient transfection

1 reference

12 December 2020

Expression of human alpha 1-antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes

1 reference

12 December 2020

Adenovirus-mediated in vivo gene transfer and expression in normal rat liver

1 reference

12 December 2020

Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy

1 reference

12 December 2020

Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified liposome method

1 reference

12 December 2020

Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells

1 reference

12 December 2020

Hepatocyte-specific binding of L/S-HBV particles expressed in insect cells

1 reference

12 December 2020

A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia

1 reference

12 December 2020

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

1 reference

12 December 2020

pH-sensitive liposomes for delivery of macromolecules into cytoplasm of cultured cells

1 reference

12 December 2020

Long-Term Improvement of Hypercholesterolemia After Ex Vivo Gene Therapy in LDLR-Deficient Rabbits

1 reference

12 December 2020

Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit).

1 reference

12 December 2020

Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.

1 reference

12 December 2020

Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector

1 reference

12 December 2020

The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants.

1 reference

12 December 2020

Retroviral-mediated gene transfer into hepatocytes in vivo

1 reference

12 December 2020

In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment

1 reference

12 December 2020

Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice

1 reference

12 December 2020

Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats

1 reference

12 December 2020

Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors

1 reference

12 December 2020

Adenovirus enhancement of transferrin-polylysine-mediated gene delivery

1 reference

12 December 2020

Frontiers in gene therapy: LDL receptor replacement for hypercholesterolemia

1 reference

12 December 2020

Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression

1 reference

12 December 2020

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

1 reference

12 December 2020

Prospects for gene therapy of familial hypercholesterolemia

1 reference

12 December 2020

Defective lipoprotein receptors and atherosclerosis. Lessons from an animal counterpart of familial hypercholesterolemia

1 reference

12 December 2020

A Modified Urokinase Plasminogen Activator Induces Liver Regeneration Without Bleeding

1 reference

12 December 2020

Retroviral gene transfer into primary hepatocytes: implications for genetic therapy of liver-specific functions

1 reference

12 December 2020

In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses.

1 reference

12 December 2020

Receptor-mediated gene delivery and expression in vivo.

1 reference

12 December 2020

The basic science of gene therapy

1 reference

12 December 2020

Regression of established macroscopic liver metastases after in situ transduction of a suicide gene

1 reference

12 December 2020

Increased expression of DNA cointroduced with nuclear protein in adult rat liver

1 reference

12 December 2020

Hepatic gene therapy: persistent expression of human alpha 1-antitrypsin in mice after direct gene delivery in vivo

1 reference

12 December 2020

A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes

1 reference

12 December 2020

Gene transfer into somatic tissues by jet injection

1 reference

12 December 2020

In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase.

1 reference

12 December 2020

Retrovirus vector-mediated gene transfer into hepatocytes.

1 reference

12 December 2020

Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes

1 reference

12 December 2020

Gene therapy: prospects for treatment of liver disease.

1 reference

12 December 2020

Tissue-specific targeting of retroviral vectors through ligand-receptor interactions

1 reference

12 December 2020

In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene

1 reference

12 December 2020

Gene expression following direct injection of DNA into liver

1 reference

12 December 2020

Ex vivo gene therapy of familial hypercholesterolemia.

1 reference

12 December 2020

Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition

1 reference

12 December 2020

Systemic gene expression after intravenous DNA delivery into adult mice

1 reference

12 December 2020

Chemical modification of an ecotropic murine leukemia virus results in redirection of its target cell specificity

1 reference

12 December 2020

Towards liver-directed gene therapy: retrovirus-mediated gene transfer into human hepatocytes

1 reference

12 December 2020

Assessment of recombinant adenoviral vectors for hepatic gene therapy

1 reference

12 December 2020

Watanabe heritable hyperlipidemic rabbit. Animal model for familial hypercholesterolemia

1 reference

12 December 2020

Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells

1 reference

12 December 2020

Persistent gene expression after retroviral gene transfer into liver cells in vivo

1 reference

12 December 2020

Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines

1 reference

12 December 2020

Efficient gene transfer into human hepatocytes by baculovirus vectors

1 reference

12 December 2020

Introduction and expression of the human insulin gene in adult rat liver

1 reference

12 December 2020

1 reference

12 December 2020

The effects of human serum and cerebrospinal fluid on retroviral vectors and packaging cell lines.

1 reference

12 December 2020

Overexpression of human methylmalonyl CoA mutase in mice after in vivo gene transfer with asialoglycoprotein/polylysine/DNA complexes

1 reference

12 December 2020

Transferrin-polycation conjugates as carriers for DNA uptake into cells

1 reference

12 December 2020

Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes

1 reference

12 December 2020

Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic mice

1 reference

12 December 2020

Factors influencing retroviral-mediated gene transfer into hepatocytes in vivo

1 reference

12 December 2020

Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice

1 reference

12 December 2020

In situ retrovirus-mediated gene transfer into dog liver

1 reference

12 December 2020

High-velocity mechanical DNA transfer of the chloramphenicolacetyl transferase gene into rodent liver, kidney and mammary gland cells in organ explants and in vivo

1 reference

12 December 2020

Receptor-mediated in vitro gene transformation by a soluble DNA carrier system

1 reference

12 December 2020

Defective and nondefective adenovirus vectors for expressing foreign genes in vitro and in vivo

1 reference

12 December 2020

Efficient in vivo transduction of the neonatal mouse liver with pseudotyped retroviral vectors.

1 reference

12 December 2020

Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

1 reference

12 December 2020

Expression of human factor IX in rabbit hepatocytes by retrovirus-mediated gene transfer: potential for gene therapy of hemophilia B.

1 reference

12 December 2020

Retroviruses: delivery vehicle to the liver

1 reference

12 December 2020

Identifiers

DOI

10.1007/S001090050023

1 reference

26 September 2017

1 reference

PubMed ID

8740651