Activation of TGF-β-induced non-Smad signaling pathways during Th17 differentiation (Q41139083)

27 September 2017

Activation of TGF-β-induced non-Smad signaling pathways during Th17 differentiation (English)

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27 September 2017

7

Ulrich Bogdahn

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27 September 2017

Maruf Hasan

1

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27 September 2017

Bernhard Neumann

2

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27 September 2017

Steffen Haupeltshofer

3

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27 September 2017

Sarah Stahlke

4

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27 September 2017

Massimo Claudio Fantini

5

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27 September 2017

Klemens Angstwurm

6

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27 September 2017

Ingo Kleiter

8

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27 September 2017

31 March 2015

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Immunology & Cell Biology

27 September 2017

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27 September 2017

93

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27 September 2017

7

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27 September 2017

662-672

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https://api.crossref.org/works/10.1038%2FICB.2015.21

27 September 2017

1 reference

Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Cellular and molecular basis for the regulation of inflammation by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Non-Smad pathways in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

SMAD2 is essential for TGF beta-mediated Th17 cell generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Smad2 positively regulates the generation of Th17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Smad4 deficiency in T cells leads to the Th17-associated development of premalignant gastroduodenal lesions in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Regulation and function of mTOR signalling in T cell fate decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

The role of PI3K in immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

PI3Kγ drives priming and survival of autoreactive CD4(+) T cells during experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

PI3Kδ drives the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting effector T cell apoptosis and promoting Th17 differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

IL-1β-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

De novo induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells in vivo following systemic antigen administration accompanied by blockade of mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Conditional inactivation of the TGF-beta type II receptor using Cre:Lox

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.21

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

21 January 2018

1 reference

12 December 2020

Akt-dependent enhanced migratory capacity of Th17 cells from children with lupus nephritis

1 reference

12 December 2020

Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin

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12 December 2020

TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells.

1 reference

12 December 2020

Cutting Edge: Trans-Signaling via the Soluble IL-6R Abrogates the Induction of FoxP3 in Naive CD4+CD25- T Cells

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12 December 2020

Identifiers

DOI

10.1038/ICB.2015.21

1 reference

27 September 2017

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