Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells (Q41464875)

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scientific article published on 17 January 2013

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English	Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells	scientific article published on 17 January 2013

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22 February 2020

Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells (English)

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22 February 2020

reactive oxygen species

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1

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22 February 2020

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Ling Xia

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22 February 2020

Howard Goldberg

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22 February 2020

Ken W Lee

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22 February 2020

Susan E Quaggin

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22 February 2020

I George Fantus

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22 February 2020

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17 January 2013

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22 February 2020

Journal of Biological Chemistry

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22 February 2020

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22 February 2020

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22 February 2020

6835-6848

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22 February 2020

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11 June 2022

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Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance

1 reference

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Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury

1 reference

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EGFR signaling promotes TGFβ-dependent renal fibrosis

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Sphingosine kinase-1 pathway mediates high glucose-induced fibronectin expression in glomerular mesangial cells

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Modulation of Nrf2 expression alters high glucose-induced oxidative stress and antioxidant gene expression in mouse mesangial cells

1 reference

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Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter

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Oxidative stress in early diabetic nephropathy: fueling the fire

1 reference

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Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes

1 reference

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The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1.

1 reference

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

1 reference

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11 June 2018

Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein

1 reference

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Subcellular localization of Nox4 and regulation in diabetes

1 reference

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Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins.

1 reference

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11 June 2018

Pathophysiology of diabetic nephropathy: involvement of multifaceted signalling mechanism

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Reduction of renal superoxide dismutase in progressive diabetic nephropathy

1 reference

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Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells

1 reference

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1 reference

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11 June 2018

Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3591594

11 June 2018

High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.

1 reference

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11 June 2018

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

1 reference

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11 June 2018

The pathogenesis of diabetic nephropathy

1 reference

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11 June 2018

Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F.

1 reference

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11 June 2018

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

1 reference

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Oxidative stress as a major culprit in kidney disease in diabetes

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11 June 2018

NOX enzymes and diabetic complications

1 reference

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11 June 2018

High glucose-induced NF-kappaB activation occurs via tyrosine phosphorylation of IkappaBalpha in human glomerular endothelial cells: involvement of Syk tyrosine kinase

1 reference

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11 June 2018

Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis

1 reference

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Diabetic nephropathy: mechanisms of renal disease progression

1 reference

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Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway

1 reference

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Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1

1 reference

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NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

1 reference

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TXNIP regulates peripheral glucose metabolism in humans

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The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange

1 reference

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1 reference

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https://pubmed.ncbi.nlm.nih.gov/23329835

12 December 2020

based on heuristic

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Selenite and selenodiglutathione: reactions with thioredoxin systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/23329835

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and propagation of glomerular mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23329835

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1074/JBC.M112.419101

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Europe PubMed Central

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22 February 2020

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22 February 2020

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22 February 2020

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