The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6. (Q41509672)

1 October 2017

The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6. (English)

1 reference

1 October 2017

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5

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1 June 2020

author name string

Shi Jiao

1

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1 June 2020

Zhen Zhang

2

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1 June 2020

Chuanchuan Li

3

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1 June 2020

Min Huang

4

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1 June 2020

Yanyan Wang

6

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1 June 2020

Xiaomin Song

7

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1 June 2020

Heng Liu

8

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1 June 2020

Chunyang Li

9

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1 June 2020

Min Chen

10

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1 June 2020

Wenjia Wang

11

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1 June 2020

Yun Zhao

12

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1 June 2020

Zhengfan Jiang

13

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1 June 2020

Hongyan Wang

14

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1 June 2020

Catherine C L Wong

15

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1 June 2020

Chen Wang

16

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1 June 2020

Zhaocai Zhou

17

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1 June 2020

language of work or name

English

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publication date

2 February 2015

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1 October 2017

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1 June 2020

volume

16

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1 June 2020

page(s)

246-257

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1 June 2020

issue

3

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Inferences, questions and possibilities in Toll-like receptor signalling

1 June 2020

cites work

1 reference

Distinct molecular mechanism for initiating TRAF6 signalling

21 January 2018

1 reference

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

21 January 2018

1 reference

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

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Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

21 January 2018

1 reference

The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors

21 January 2018

1 reference

HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination

21 January 2018

1 reference

UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination

21 January 2018

1 reference

CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization

21 January 2018

1 reference

Structural mechanism of CCM3 heterodimerization with GCKIII kinases

21 January 2018

1 reference

Cloning and characterization of MST4, a novel Ste20-like kinase

21 January 2018

1 reference

MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway

21 January 2018

1 reference

Structure of MST2 SARAH domain provides insights into its interaction with RAPL.

21 January 2018

1 reference

A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer

21 January 2018

1 reference

Striatins contain a noncanonical coiled coil that binds protein phosphatase 2A A subunit to form a 2:2 heterotetrameric core of striatin-interacting phosphatase and kinase (STRIPAK) complex.

21 January 2018

1 reference

PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway

21 January 2018

1 reference

Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex

21 January 2018

1 reference

Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization.

21 January 2018

1 reference

Structure of the MST4 in complex with MO25 provides insights into its activation mechanism

21 January 2018

1 reference

Structural basis for the unique heterodimeric assembly between cerebral cavernous malformation 3 and germinal center kinase III

21 January 2018

1 reference

A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha

21 January 2018

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Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

21 January 2018

1 reference

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6.

21 January 2018

1 reference

Molecular basis for CD40 signaling mediated by TRAF3

21 January 2018

1 reference

A universal role for MyD88 in TLR/IL-1R-mediated signaling

21 January 2018

1 reference

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

1 reference

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways

21 January 2018

1 reference

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

21 January 2018

1 reference

Ubiquitin chain cleavage: CYLD at work

21 January 2018

1 reference

A20: from ubiquitin editing to tumour suppression

21 January 2018

1 reference

The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal

21 January 2018

1 reference

STRIPAK components determine mode of cancer cell migration and metastasis.

21 January 2018

1 reference

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

21 January 2018

1 reference

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.

21 January 2018

1 reference

MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling

21 January 2018

1 reference

The E3 ligase TRAF6 regulates Akt ubiquitination and activation

21 January 2018

1 reference

TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.

21 January 2018

1 reference

Inhibition of influenza virus production in virus-infected mice by RNA interference

21 January 2018

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The role of the Wnt family of secreted proteins in rat oval "stem" cell-based liver regeneration: Wnt1 drives differentiation

21 January 2018

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Knockdown of connective tissue growth factor by plasmid-based short hairpin RNA prevented pulmonary vascular remodeling in cigarette smoke-exposed rats

21 January 2018

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A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress

21 January 2018

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Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver

21 January 2018

1 reference

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

21 January 2018

1 reference

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

Negative feedback regulation of NF-κB action by CITED2 in the nucleus

21 January 2018

1 reference

Kinetics of TNF, IL-6, and IL-8 gene expression in LPS-stimulated human whole blood

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25642822