Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation (Q41591704)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

author name string

Karin Schilbach

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Mohammed Alkhaled

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Christian Welker

3

1 reference

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18 February 2020

Franziska Eckert

4

1 reference

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18 February 2020

Gregor Blank

5

1 reference

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18 February 2020

Hendrik Ziegler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Marco Sterk

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Friederike Müller

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Katja Sonntag

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Thomas Wieder

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Heidi Braumüller

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Julia Schmitt

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Sabine Schleicher

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Christian Seitz

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Annika Erbacher

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Bernd J Pichler

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Hartmut Müller

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Robert Tighe

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Annick Lim

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Stephen D Gillies

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Wolfgang Strittmatter

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Martin Röcken

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Rupert Handgretinger

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

publication date

19 March 2015

1 reference

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18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

page(s)

e1014760

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

p21WAF1 and tumourigenesis: 20 years after

18 February 2020

cites work

1 reference

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IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

6 June 2018

1 reference

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

6 June 2018

1 reference

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Tumor-associated macrophages and survival in classic Hodgkin's lymphoma

6 June 2018

1 reference

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Cellular senescence in the development and treatment of cancer.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Therapeutic antibodies: successes, limitations and hopes for the future

6 June 2018

1 reference

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p21 in cancer: intricate networks and multiple activities

6 June 2018

1 reference

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Trophic macrophages in development and disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Late developmental plasticity in the T helper 17 lineage

6 June 2018

1 reference

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A novel approach for quantification of KIR expression in healthy donors and pediatric recipients of hematopoietic SCTs

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Prognostic factors in metastatic rhabdomyosarcomas: results of a pooled analysis from United States and European cooperative groups.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Up on the tightrope: natural killer cell activation and inhibition

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Heterochromatin and its relationship to cell senescence and cancer therapy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

CD4 cells can be more efficient at tumor rejection than CD8 cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Identification and epitope enhancement of a PAX-FKHR fusion protein breakpoint epitope in alveolar rhabdomyosarcoma cells created by a tumorigenic chromosomal translocation inducing CTL capable of lysing human tumors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Regulation of growth arrest in senescence: telomere damage is not the end of the story

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Human LATS1 is a mitotic exit network kinase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Natural-killer cells and dendritic cells: "l'union fait la force".

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Intrinsic tumour suppression

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Desmin: a major intermediate filament protein essential for the structural integrity and function of muscle

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Tolerance, not immunity, crucially depends on IL-2.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Interleukin-12 and the regulation of innate resistance and adaptive immunity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Characterization of a phage display-derived human monoclonal antibody (NHS76) counterpart to chimeric TNT-1 directed against necrotic regions of solid tumors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites

6 June 2018

1 reference

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Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: ability to maintain IFN-gamma induction is associated with clinical response

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

IFN-gamma induction of p21(WAF1) is required for cell cycle inhibition and suppression of apoptosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Implication of gammadelta T cells in the human immune response to cytomegalovirus

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Cell cycle exit upon myogenic differentiation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Interleukin 12 primes macrophages for nitric oxide production in vivo and restores depressed nitric oxide production by macrophages from tumor-bearing mice: implications for the antitumor activity of interleukin 12 and/or interleukin 2.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Expression of desmin and myoglobin in rhabdomyosarcomas and in developing skeletal muscle

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

T-helper-1-cell cytokines drive cancer into senescence

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

TH1 predominance is associated with improved survival in pediatric medulloblastoma patients

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Adaptive immunity maintains occult cancer in an equilibrium state

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Expression of CD161 (NKR-P1A) defines subsets of human CD4 and CD8 T cells with different functional activities.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Macrophages as effector cells in interleukin 12-induced T cell-dependent tumor rejection

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping. Correlation with immune status.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485786

Induction of p21 (WAF-1/CIP1) during differentiation

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26140238

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26140238

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Invariant or highly conserved TCR alpha are expressed on double-negative (CD3+CD4-CD8-) and CD8+ T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26140238

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1080/2162402X.2015.1014760

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26140238%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PubMed publication ID

26140238

1 reference