Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. (Q41597377)

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24 March 2020

title

Electron cryo-microscopy structure of the mechanotransduction channel NOMPC (English)

1 reference

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cryogenic electron microscopy

24 March 2020

main subject

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1 reference

2

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24 March 2020

author name string

Peng Jin

1

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24 March 2020

Yanmeng Guo

3

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24 March 2020

Wei Zhang

4

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24 March 2020

Zhenhao Guo

5

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24 March 2020

Walter Huynh

6

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24 March 2020

Shenping Wu

7

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24 March 2020

Shan Meltzer

8

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24 March 2020

Tong Cheng

9

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24 March 2020

Lily Yeh Jan

10

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24 March 2020

Yuh-Nung Jan

11

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24 March 2020

Yifan Cheng

12

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24 March 2020

language of work or name

English

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publication date

26 June 2017

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24 March 2020

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24 March 2020

volume

547

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24 March 2020

issue

7661

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24 March 2020

page(s)

118-122

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MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

24 March 2020

cites work

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6 June 2018

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Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3

6 June 2018

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Crystal structure of the epithelial calcium channel TRPV6

6 June 2018

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TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

6 June 2018

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Structure of the full-length TRPV2 channel by cryo-EM.

6 June 2018

1 reference

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Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension.

6 June 2018

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Cryo-electron microscopy structure of the TRPV2 ion channel

6 June 2018

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Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist

6 June 2018

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6 June 2018

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Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel

6 June 2018

1 reference

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EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.

6 June 2018

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Structure of the TRPA1 ion channel suggests regulatory mechanisms

6 June 2018

1 reference

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L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel

6 June 2018

1 reference

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Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels

6 June 2018

1 reference

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Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

6 June 2018

1 reference

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Structural basis of diverse membrane target recognitions by ankyrins

6 June 2018

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A robust pipeline for rapid production of versatile nanobody repertoires

6 June 2018

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Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

6 June 2018

1 reference

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Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

6 June 2018

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TRPV1 structures in distinct conformations reveal activation mechanisms

6 June 2018

1 reference

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Structure of the TRPV1 ion channel determined by electron cryo-microscopy

6 June 2018

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Quantifying the local resolution of cryo-EM density maps

6 June 2018

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PRIME: probabilistic initial 3D model generation for single-particle cryo-electron microscopy

6 June 2018

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A NOMPC-dependent membrane-microtubule connector is a candidate for the gating spring in fly mechanoreceptors.

6 June 2018

1 reference

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Stiffened lipid platforms at molecular force foci

6 June 2018

1 reference

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Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation

6 June 2018

1 reference

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6 June 2018

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RELION: implementation of a Bayesian approach to cryo-EM structure determination

6 June 2018

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Prevention of overfitting in cryo-EM structure determination

6 June 2018

1 reference

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Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome

6 June 2018

1 reference

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Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel

6 June 2018

1 reference

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Visualizing proteins and macromolecular complexes by negative stain EM: from grid preparation to image acquisition.

6 June 2018

1 reference

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The crystal structure of a voltage-gated sodium channel

6 June 2018

1 reference

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Computer control of microscopes using µManager

6 June 2018

1 reference

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The role of the TRP channel NompC in Drosophila larval and adult locomotion

6 June 2018

1 reference

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Features and development of Coot

6 June 2018

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Eukaryotic mechanosensitive channels

6 June 2018

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

6 June 2018

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

6 June 2018

1 reference

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Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

6 June 2018

1 reference

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6 June 2018

1 reference

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A C. elegans stretch receptor neuron revealed by a mechanosensitive TRP channel homologue

6 June 2018

1 reference

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Automated electron microscope tomography using robust prediction of specimen movements

6 June 2018

1 reference

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Hypothesis: a helix of ankyrin repeats of the NOMPC-TRP ion channel is the gating spring of mechanoreceptors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669069

NompC TRP channel required for vertebrate sensory hair cell mechanotransduction.

6 June 2018

1 reference

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A Drosophila mechanosensory transduction channel

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669069

SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5669069

NompC TRP channel is essential for Drosophila sound receptor function

6 June 2018

1 reference

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Nanospring behaviour of ankyrin repeats.

19 August 2018

1 reference

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19 August 2018

Identifiers

DOI

10.1038/NATURE22981

1 reference

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Dimensions Publication ID

24 March 2020

0 references

1 reference

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24 March 2020

PubMed publication ID

28658211

1 reference