Protein kinase C-θ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway (Q41613842)

5 October 2017

Protein kinase C-θ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway (English)

1 reference

5 October 2017

1 reference

Jian Ma

1

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5 October 2017

Yan Ding

2

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5 October 2017

Xianfeng Fang

3

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5 October 2017

Ruiqing Wang

4

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5 October 2017

Zuoming Sun

5

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5 October 2017

language of work or name

English

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publication date

25 April 2012

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5 October 2017

Journal of Immunology

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5 October 2017

188

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5 October 2017

11

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5 October 2017

5337-5347

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describes a project that uses

5 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3484896/fullTextXML

inferred from PubMed Central ID database lookup

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CD28 controls differentiation of regulatory T cells from naive CD4 T cells

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation

6 June 2018

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6 June 2018

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PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways

6 June 2018

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6 June 2018

1 reference

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FoxO: linking new signaling pathways

6 June 2018

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Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Identification of a conserved motif required for mTOR signaling

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Protein kinase C(theta) in T cell activation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Protein kinase Ctheta: a new essential superstar on the T-cell stage

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Protein kinase C-alpha overexpression stimulates Akt activity and suppresses apoptosis induced by interleukin 3 withdrawal

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Mechanism of activation of protein kinase B by insulin and IGF-1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Protein kinase Ctheta controls Th1 cells in experimental autoimmune encephalomyelitis.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484896

Comment on "PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation"

4 November 2018

1 reference

12 December 2020

The critical role of protein kinase C-theta in Fas/Fas ligand-mediated apoptosis

1 reference

12 December 2020

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

1 reference

12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

12 December 2020

T-cell antigen receptor signal transduction

1 reference

12 December 2020

Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C theta

1 reference

12 December 2020

SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1102979

1 reference

5 October 2017

1 reference

5 October 2017

PubMed publication ID

22539794

1 reference